Prevention of ultraviolet-induced skin pigmentation

Photodermatology, Photoimmunology & Photomedicine
Dominique Moyal

Abstract

Exposure to ultraviolet (UV) radiation increases skin pigmentation and usually results in an even darkening of the skin. However, it may also occasionally lead to the development of hyperpigmented lesions due to a local overproduction of pigment. Skin pigmentation is induced both by UVB and UVA rays. The in vivo protection by sunscreens against pigmentation was studied using the determination of a level of protection against pigmentation based on the standardized sun protection factor (SPF) test method. The method includes delayed UVB and UVA pigmentations. The level of prevention against pigmentation was determined 7 days after exposure to solar-simulated radiation by visual assessment. It was calculated using the ratio of the minimal pigmenting dose on protected skin to the minimal pigmenting dose on unprotected skin. Broadspectrum UVB/UVA filters, Mexoryl SX and Mexoryl XL, and complete formula were tested. Protection against pigmentation correlates with the concentration of Mexoryl SX. The levels of protection obtained show a synergetic effect of Mexoryl SX when associated with Mexoryl XL. When different products having the same SPF (same protection against erythema) and different levels of UVA protection are compared, only...Continue Reading

References

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Citations

Jun 22, 2012·Indian Journal of Dermatology, Venereology and Leprology·Dominique Moyal
Feb 5, 2011·Journal of the American Academy of Dermatology·Divya R Sambandan, Desiree Ratner
Oct 23, 2008·Clinics in Dermatology·Salvador GonzálezYolanda Gilaberte-Calzada
Aug 19, 2007·Lancet·Stephan LautenschlagerMark R Pittelkow
Nov 29, 2005·Dermatologic Clinics·Chanisada TuchindaAndré Rougier
Mar 4, 2008·Journal of the European Academy of Dermatology and Venereology : JEADV·J GengX-D Chen
Jul 26, 2011·International Journal of Dermatology·Cynthia Gonzales-CastañedaGustavo Francisco Gonzales
Sep 27, 2014·International Journal of Cosmetic Science·C Stiefel, W Schwack
Apr 14, 2015·Mutation Research. Genetic Toxicology and Environmental Mutagenesis·Guillermo M Zúñiga-GonzálezMartha P Gallegos-Arreola
Oct 1, 2016·Indian Journal of Dermatology·Stephanie NouveauChitra Shivanand Nayak
Oct 30, 2016·Journal of Photochemistry and Photobiology. B, Biology·Guillermo M Zúñiga-GonzálezMartha P Gallegos-Arreola
Nov 24, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·A PacificoA Morrone
Sep 7, 2007·Plastic and Reconstructive Surgery·Gehaan D'SouzaUNKNOWN Plastic Surgery Educational Foundation Technology Assessment Committee
Feb 8, 2020·Indian Journal of Dermatology·Sakeena FatimaIltefat H Hamzavi
Jan 27, 2020·Skin Pharmacology and Physiology·Birgit GarbeNicole Braun

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