Prevention research strategies

Nutrition Reviews
L H Kuller

Abstract

Prevention of disease is the only method to substantially reduce morbidity and mortality in a population. The two key determinants of disease are the levels of risk factors/determinants and the adherence to efficacious therapies, and there are two approaches to these: public health and preventive medicine. Clinical trials remain the cornerstone for evaluating new approaches. Effectiveness studies are required to evaluate the best approaches to deliver efficacious therapies; public health and preventive medicine programs must include the entire population, and can be costly. Environmental changes have greater benefits and a greater likelihood of reaching large segments of the population, but the preventive medicine approach is better for high-risk diseases. New risk factors and diseases evolve from the upper to lower social classes, while preventive therapies evolve from the upper to lower education groups.

References

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Citations

Oct 24, 2007·Hypertension·Lewis H Kuller
Aug 12, 2008·Journal of the American College of Nutrition·Arrigo F G CiceroUNKNOWN EUROLIVE Study Group
Dec 31, 2015·Frontiers of Medicine·Shirin AnilRedhwan Ahmed Al-Naggar
Oct 13, 2007·Journal of Proteome Research·Serge RezziSunil Kochhar

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