Preventive and Therapeutic Effects of Chinese Herbal Compounds against Hepatocellular Carcinoma

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Bing HuLing Xu

Abstract

Traditional Chinese Medicines, unique biomedical and pharmaceutical resources, have been widely used for hepatocellular carcinoma (HCC) prevention and treatment. Accumulated Chinese herb-derived compounds with significant anti-cancer effects against HCC have been identified. Chinese herbal compounds are effective in preventing carcinogenesis, inhibiting cell proliferation, arresting cell cycle, inducing apoptosis, autophagy, cell senescence and anoikis, inhibiting epithelial-mesenchymal transition, metastasis and angiogenesis, regulating immune function, reversing drug resistance and enhancing the effects of chemotherapy in HCC. This paper comprehensively reviews these compounds and their effects on HCC. Finally, the perspectives and rational application of herbal compounds for HCC management are discussed.

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Citations

Feb 20, 2018·Evidence-based Complementary and Alternative Medicine : ECAM·Li-Ling ShenDonald E Morisky
Jan 23, 2020·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·B WangX Bu
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Aug 17, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chi-Chang ChangJer-Yiing Houng
Oct 6, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Zhulin WuLisheng Peng
Jan 8, 2021·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Wei-Chung HsuChih-Yang Huang
May 6, 2021·International Journal of Molecular Sciences·So Young KimYung Hyun Choi
Dec 19, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Honghua YanSoon-Sun Hong

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Methods Mentioned

BETA
electrophoresis

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