PMID: 2193927Jul 1, 1990

Prey-derived signals regulating duration of the developmental growth phase of Bdellovibrio bacteriovorus

Journal of Bacteriology
K M Gray, E G Ruby

Abstract

The filamentous elongation typical of growth-phase cells of the predatory bacterium Bdellovibrio bacteriovorus is mediated by regulatory signals that are derived from the prey cell itself. These signals regulate the differentiation of growth-phase cells into the attack phase and appear to be required for continued filamentous growth by prey-dependent wild-type bdellovibrios and their prey-independent mutant derivatives alike. Using a prey-independent bdellovibrio strain, we have developed an assay for the detection and quantification of the growth-extending signal activity present in extracts of prey cells. This prey-derived regulatory activity was shown to be independent of its nutritional contribution to the bdellovibrios and was found to occur in heat-stable, proteinlike compounds of a variety of native molecular weights within the soluble fraction of extracts from both gram-negative and gram-positive bacteria.

Citations

Jul 31, 2007·Future Microbiology·Eckhard StrauchMichael Linscheid
Feb 22, 2017·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Juan A Arias Del AngelMariana Benítez
Oct 22, 2015·Proceedings of the National Academy of Sciences of the United States of America·Or RotemEdouard Jurkevitch
Sep 23, 1997·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J M Frade, T M Michaelidis
May 12, 2019·Applied and Environmental Microbiology·Łukasz MakowskiJolanta Zakrzewska-Czerwińska

Related Concepts

Bdellovibrio
DNA, Bacterial
Gram-Negative Bacteria
Saccharomyces cerevisiae

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