Primary adenocarcinoma of third and fourth portions of duodenum. Favorable prognosis after resection

Archives of Surgery
J A LowellJ W Braasch


Duodenal adenocarcinoma, a rare malignant lesion, is associated with a poor 5-year survival. Few series have addressed differences between resectable tumors of the proximal and distal duodenum. We reviewed records of 17 consecutive patients with adenocarcinoma of the duodenum who underwent resection: 10 had adenocarcinoma of the proximal duodenum, and seven had tumors of the distal duodenum. Most patients underwent pancreatoduodenectomy. Five patients with adenocarcinoma of the distal duodenum underwent segmental resection. No perioperative deaths occurred. Six of 10 patients with proximal tumors died of metastatic disease. Of the seven patients with tumors of the distal duodenum, five are alive without evidence of disease, and two died of unrelated causes. The survival of patients with adenocarcinoma of the distal duodenum is surprisingly good, and segmental resection is the procedure of choice.


Apr 8, 2014·World Journal of Gastroenterology : WJG·Yi-Bin XieYan-Tao Tian
Aug 28, 2014·Annals of Surgical Oncology·Jordan M CloydGeorge A Poultsides
Aug 1, 1995·Journal of Gastroenterology·T SatoT Matsushiro
Apr 29, 2009·Journal of Gastrointestinal Cancer·Shao-Liang HanSheng-Hong Lan
Jun 11, 2009·Journal of Gastrointestinal Cancer·Shao-Liang HanSheng-Hong Lan
May 1, 2010·Journal of Gastrointestinal Cancer·Shao-Liang HanSheng-Hong Lan
Jan 5, 2001·The Surgical Clinics of North America·J E GervasoniB Cady
May 28, 2013·International Journal of Surgery Case Reports·Toru NakanoNoriaki Ohuchi
Apr 29, 2015·International Journal of Surgery·Francisco J García-MolinaIosvany Rivero-Henández
Mar 30, 2016·World Journal of Gastrointestinal Surgery·Jordan M CloydBrendan C Visser
Aug 13, 1999·The American Journal of Gastroenterology·B ZhaoM Makuuchi
Feb 16, 2006·World Journal of Surgery·Ting-Jung WuMiin-Fu Chen
Dec 15, 2011·Annals of Surgical Oncology·George A PoultsidesRichard D Schulick
Feb 22, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Edwin O OnkendiFlorencia G Que
Jun 1, 1995·Postgraduate Medical Journal·O A AdedejiM Garcia-Zarco
Oct 1, 1994·Scandinavian Journal of Gastroenterology·C J Tsai
Apr 2, 2013·The Indian Journal of Surgery·Ajay Mandal, Sarfaraj Baig
Jan 1, 1994·Annals of Surgical Oncology·G BarnesS A Curley
Jan 23, 1999·Journal of Clinical Gastroenterology·Y TanakaY Esaki
Aug 2, 2012·The Indian Journal of Surgery·Sarfaraz Jalil Baig
Sep 26, 2012·International Journal of Molecular Medicine·Jing-Xia ChangGuo-Jun Zhang
Jan 3, 2021·International Journal of Clinical Oncology·Pipit BurasakarnJapan Duodenal Cancer Guideline Committee
Sep 30, 2019·Cirugía española·Josefina López-DomínguezJuan Fabregat

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.