Primary afferent fibers establish dye-coupled connections in the frog central nervous system

Brain Research Bulletin
Tímea Bacskai, Clara Matesz

Abstract

Neurobiotin and Lucifer yellow, indicators of gap junctional coupling, were applied to primary afferent fibers of the frog. Following application of tracers to cervical or lumbar dorsal root fibers, a large number of labeled granule cells were detected in the corpus cerebelli, the brainstem, and the spinal cord. The vestibular nerve was found to be in dye-coupled connection with the granule cells of the auricular lobe of the cerebellum. After application of the tracers to the trigeminal nerve, elicited dye-coupled neurons located mainly in the termination area of the descending limb of the mesencephalic trigeminal nucleus. In control experiments with biotinylated dextrane amine, only primary afferent fibers were labeled. Our results suggest that gap junctional coupling exists between primary afferent fibers and their postsynaptic targets in the frog.

References

Mar 1, 1978·The Journal of Comparative Neurology·C Matesz, G Székely
Feb 1, 2000·Trends in Neurosciences·J L Perez Velazquez, P L Carlen

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Citations

Sep 1, 2005·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Ruey-Jane FanW Otto Friesen
Nov 12, 2003·Respiratory Physiology & Neurobiology·Rachel E Winmill, Michael S Hedrick

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