Primary aldosteronism and thyroid disorders in atrial fibrillation: A Swedish nationwide case-control study

European Journal of Preventive Cardiology
Georgios MourtzinisKarin Manhem

Abstract

Background Atrial fibrillation is associated with hyperthyroidism. Patients with primary aldosteronism have an increased prevalence of atrial fibrillation. However, the prevalence of primary aldosteronism in the atrial fibrillation population is unknown. Aim This nationwide case-control study aimed to compare the prevalence of primary aldosteronism and thyroid disorders in patients with atrial fibrillation with that of age- and sex-matched controls. Methods We identified all atrial fibrillation cases in Sweden between 1987 and 2013 ( n = 713,569) by using the Swedish National Patient Register. A control cohort without atrial fibrillation was randomly selected from the Swedish Total Population Register with a case to control ratio of 1:2. This control cohort was matched for age, sex and place of birth ( n = 1,393,953). Results The prevalence of primary aldosteronism in December 2013 was 0.056% in the atrial fibrillation cohort and 0.024% in controls. At the same time, the prevalence of hypothyroidism was 5.9% in the atrial fibrillation cohort and 3.7% in controls. The prevalence of hyperthyroidism was 2.3% in the atrial fibrillation cohort and 0.8% in controls. Conclusion This study shows, for the first time, a doubled prevalenc...Continue Reading

References

Jun 30, 2000·Clinical Cardiology·B M FadelK D Burman
Feb 15, 2001·The New England Journal of Medicine·I Klein, K Ojamaa
Apr 20, 2005·Journal of the American College of Cardiology·Paul MilliezJean-Jacques Mourad
Oct 6, 2005·European Heart Journal·Robby NieuwlaatUNKNOWN European Heart Survey Investigators
Aug 10, 2006·The Journal of Clinical Hypertension·L Michael PrisantAnthony L Mulloy
Dec 13, 2006·Journal of the American College of Cardiology·Gian Paolo RossiUNKNOWN PAPY Study Investigators
Mar 20, 2008·The Journal of Clinical Endocrinology and Metabolism·K WustmannE Delacrétaz
Apr 4, 2009·Thyroid Research·Agata Bielecka-DabrowaMaciej Banach
Jun 11, 2011·BMC Public Health·Jonas F LudvigssonPetra Otterblad Olausson
Aug 6, 2011·European Heart Journal·Jan-Christian ReilHans-Ruprecht Neuberger
Dec 3, 2011·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·A Hannemann, H Wallaschofski
May 23, 2012·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Carina LammersCarsten Zobel
Sep 11, 2012·BMC Endocrine Disorders·Helga Agusta SigurjonsdottirGudmundur Johannsson
Nov 29, 2012·BMJ : British Medical Journal·Christian SelmerGunnar Hilmar Gislason
Aug 29, 2013·Stroke; a Journal of Cerebral Circulation·Staffan BjörckLennart Bergfeldt
Sep 17, 2013·Circulation. Arrhythmia and Electrophysiology·Youhua ZhangA Martin Gerdes
Dec 18, 2013·American Heart Journal·Eun-Jeong KimJared W Magnani
Jan 16, 2014·The Journal of Clinical Endocrinology and Metabolism·Ane Garmendia MadariagaJuan C Galofré
Mar 26, 2014·The American Journal of Medicine·Ira Martin Grais, James R Sowers
Jul 25, 2014·The American Journal of Medicine·Helene BruereNicolas Clementy
Apr 2, 2015·International Journal of Cardiology·Lei LiuYue Li
May 14, 2016·The Journal of Clinical Endocrinology and Metabolism·Sabine C KäyserJaap Deinum
Aug 4, 2016·Endocrine-related Cancer·Ravi Kumar DuttaOliver Gimm
Nov 12, 2016·Thyroid : Official Journal of the American Thyroid Association·Sergio ValdésGemma Rojo-Martínez
Sep 22, 2017·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·Georgios MourtzinisKarin Manhem

❮ Previous
Next ❯

Citations

Mar 17, 2018·European Journal of Preventive Cardiology·Iana Simova, Iskren Garvanski
Apr 28, 2018·European Journal of Preventive Cardiology·Massimo F Piepoli
Jan 9, 2020·Journal of Hypertension·Athanasios Manolis, Michael Doumas

❮ Previous
Next ❯

Software Mentioned

SAS
PAPPHY

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.