PMID: 9416489Jan 7, 1998Paper

Primary alveolar soft-part sarcoma of the mediastinum: a clinicopathological and immunohistochemical study of two cases

Histopathology
D B FliederS Suster

Abstract

Primary alveolar soft part sarcomas originating within the thoracic cavity are rare. The cases herein described highlight the ubiquitous distribution of this neoplasm and the importance of considering this tumour in the differential diagnosis of mediastinal tumours. Two cases of alveolar soft-part sarcoma of the mediastinum are presented. The patients are two men of 22 and 23 years of age. Clinically, the patients presented with symptoms of chest pain. One tumour was in the anterior mediastinum while the second tumour was in the posterior mediastinum. Even though the bulk of the tumours were in mediastinal locations, both patients had pulmonary metastases at the time of diagnosis. Histologically, both tumours showed the classic morphology of alveolar soft part sarcoma, i.e. a proliferation of large polygonal cells with round to oval nuclei, prominent nucleoli and moderate amounts of eosinophilic cytoplasm arranged in a prominent alveolar pattern. Periodic acid-Schiff stains showed the characteristic diastase-resistant intracytoplasmic crystals. Immunohistochemical studies showed focal myoglobin reactivity in one case, while cytokeratin, vimentin, S100 protein, chromogranin, synaptophysin, neurofilaments, leu-enkephalin, desmin,...Continue Reading

Citations

Dec 15, 2006·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·David B CohenMarc S Schwartz
Jun 12, 2009·World Journal of Surgical Oncology·Mohammed N BaniHani, Abdel Rahman A Al Manasra
Feb 22, 2014·Virchows Archiv : an International Journal of Pathology·Annikka Weissferdt, Cesar A Moran
Apr 11, 2014·Journal of Orthopaedics·Aaron W JamesSarah M Dry
Nov 7, 1998·Ultrastructural Pathology·N G Ordóñez, B Mackay
Nov 7, 1998·Ultrastructural Pathology·I A CardinalliG R Dickersin
Jul 14, 2009·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Emily WardWilliam C Torreggiani
Jul 12, 2011·Pediatric Blood & Cancer·Nuria CondeJaume Mora
Dec 16, 2004·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Kelen Christine do Nascimento SouzaAdriano Mota Loyola
Sep 12, 2015·Virchows Archiv : an International Journal of Pathology·Michael A den BakkerPhilipp Ströbel
Aug 25, 2015·Surgical Pathology Clinics·Aaron W James, Sarah M Dry
Mar 31, 2004·The Journal of Thoracic and Cardiovascular Surgery·Pier Luigi FilossoMaurizio Mancuso
Apr 3, 2008·Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B·Li Juan PangFeng Li
Jun 24, 2008·Fetal and Pediatric Pathology·Pawini KhannaEnid Gilbert-Barness
Aug 29, 2017·Case Reports in Cardiology·Abhinav TiwariHermann Simo
Mar 23, 2017·SAGE Open Medical Case Reports·Yohei KamedaMunetaka Masuda
Sep 25, 2018·American Journal of Clinical Pathology·Neda Kalhor, Cesar A Moran
Apr 23, 2009·The American Journal of Dermatopathology·Denisa KacerovskaDmitry V Kazakov
Apr 26, 2014·Clinics and Practice·Ryan SchenningKatharine Hopkins
Aug 6, 2021·Virchows Archiv : an International Journal of Pathology·Atsuko KasajimaGünter Klöppel
May 30, 2021·Advances in Anatomic Pathology·Joon Hyuk Choi, Jae Y Ro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Steven V RichardsStephen W Bayles
Skull Base : Official Journal of North American Skull Base Society ... [et Al.]
David B CohenMarc S Schwartz
European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Tahir AltuğSergülen Dervişoğlu
© 2021 Meta ULC. All rights reserved