Primary and metastatic cancer of the parotid: comparison of clinical behavior in 232 cases

The Laryngoscope
Luc P BronChristopher J O'Brien

Abstract

Parotid malignancy may develop as a primary cancer of salivary tissue or by metastatic involvement of parotid lymph nodes. The aim of the study was to compare the clinical behavior of primary and metastatic parotid cancers by analyzing patterns of treatment failure and clinical outcomes. Retrospective review of clinical and pathologic data prospectively accessioned onto a computerized database. A prospectively documented series of 232 parotidectomies carried out for treatment of cancer from 1988 to 1999 was reviewed. There were 177 male and 55 female patients with a median age of 65 years (age range, 17-97 y). Median follow-up time was 4 years. Pathological groups included 54 patients with primary parotid cancer, 101 with metastatic cutaneous squamous cell carcinoma, 69 with metastatic melanoma, and 8 with other metastatic cancers. Neck nodes were clinically positive in 12 patients with primary cancer, 24 patients with squamous cell carcinoma, 16 with melanoma, and 2 with other metastatic malignancies. Conservative parotidectomy, preserving the main trunk of the facial nerve, was performed in 185 patients, and 47 patients had a radical parotidectomy sacrificing the facial nerve. There were 54 therapeutic and 110 elective neck d...Continue Reading

References

Oct 1, 1975·American Journal of Surgery·R H SpiroE W Strong
Oct 1, 1975·American Journal of Surgery·J E WoodsO H Beahrs
Nov 1, 1991·Archives of Otolaryngology--head & Neck Surgery·R A FrankenthalerH Goepfert
Jan 1, 1991·Seminars in Surgical Oncology·R H Spiro
Oct 1, 1988·American Journal of Surgery·C B Caldwell, R H Spiro
Apr 1, 1986·Zeitschrift für Stomatologie
Nov 1, 1986·Head & Neck Surgery·C J O'BrienW A Maddox
Oct 1, 1986·International Journal of Radiation Oncology, Biology, Physics·P J Fitzpatrick, C Theriault
Sep 1, 1983·International Journal of Radiation Oncology, Biology, Physics·D McNaneyM J Oswald
Nov 1, 1982·Archives of Otolaryngology·O M Guillamondegui
Oct 1, 1981·American Journal of Surgery·G L Jackson, A J Ballantyne
Nov 1, 1995·American Journal of Surgery·V G KhuranaN A Packham
Jan 15, 1995·International Journal of Radiation Oncology, Biology, Physics·J A MeeuwissenJ H Kearsley
Nov 1, 1994·Annals of Surgical Oncology·L M ToonkelV Dembrow
Nov 1, 1994·American Journal of Surgery·C J O'BrienV Malka
May 1, 1993·Archives of Otolaryngology--head & Neck Surgery·R A FrankenthalerH Goepfert
Jun 5, 1998·British Journal of Plastic Surgery·C M MalataJ V Soames
Jul 15, 1998·Head & Neck·J O delCharcoN P Mendenhall
Sep 12, 1998·Otolaryngologic Clinics of North America·J E Medina
Jul 26, 2000·Acta Oto-laryngologica. Supplementum·S CharabiJ Thomsen
Mar 10, 2001·American Journal of Clinical Oncology·B D LawendaP A Johnstone
Sep 25, 2001·The Laryngoscope·E HocwaldJ R Jacobs

❮ Previous
Next ❯

Citations

Dec 20, 2011·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Małgorzata WierzbickaGrażyna Bem
Feb 10, 2007·Current Oncology Reports·Joseph M Scianna, Guy J Petruzzelli
Nov 20, 2008·Journal of Gastrointestinal Cancer·Despina SpyropoulouDimitrios Kardamakis
Dec 1, 2006·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Susana Canales Ugarte, Javier Cassinello Espinosa
Jul 3, 2010·Head and Neck Pathology·Leon Barnes
Apr 2, 2013·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Giuseppe MercanteGiuseppe Spriano
Dec 5, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michel NuyensPeter Zbären
Jan 10, 2009·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ali RazfarFrederic W-B Deleyiannis
Apr 1, 2012·Indian Journal of Nuclear Medicine : IJNM : the Official Journal of the Society of Nuclear Medicine, India·Sumeet G DuaVenkatesh Rangarajan
May 13, 2014·American Journal of Otolaryngology·Michael J PfistererJean Anderson Eloy
Apr 14, 2007·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Juan-Carlos Martinez, Jonathan L Cook
May 31, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Sylvain MorinièreJean Lacau St Guily
Apr 29, 2008·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Roderik MrenaAntti A Mäkitie
May 27, 2011·International Journal of Oral and Maxillofacial Surgery·P Lequerica-FernándezJ C de Vicente
Jan 27, 2009·The British Journal of Oral & Maxillofacial Surgery·Margarita MesaJuan Piñas
Mar 22, 2008·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Menachem GrossRon Eliashar
May 28, 2005·Head & Neck·Suimin Qiu, Mario A Luna
Feb 9, 2008·Cancer·William M MendenhallNancy P Mendenhall
Feb 14, 2006·Head & Neck·Yu-Lan Mary YingEugene N Myers
Jun 4, 2013·Head & Neck·Cara C CockerillMichael E Kupferman
Feb 28, 2006·American Journal of Otolaryngology·W Cooper ScurryFred G Fedok
Apr 5, 2016·Otolaryngologic Clinics of North America·Michele M Gandolfi, William Slattery
Sep 25, 2015·The Journal of Laryngology and Otology·C MukherjeeH Ahluwalia
Mar 26, 2015·Head and Neck Pathology·Rebecca D Chernock, James S Lewis
Jun 28, 2011·The American Journal of Pathology·Yoshitsugu MitaniAdel K El-Naggar
Feb 23, 2010·Otolaryngologia polska. The Polish otolaryngology·Stanisław ZyłkaStanisław Bień
Feb 5, 2013·Otolaryngologia polska. The Polish otolaryngology·Maciej PabiszczakWitold Szyfter
Jul 6, 2017·The Journal of Laryngology and Otology·A C CoombsR Allison
Oct 1, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Christopher C XiaoTerry A Day
May 10, 2017·Head & Neck·Aileen P WertzScott A McLean
Mar 14, 2018·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Nir HirshorenBenjamin J Dixon
Oct 3, 2017·Cytopathology : Official Journal of the British Society for Clinical Cytology·A BayramD Yılmazbayhan
Oct 28, 2019·Journal of Surgical Oncology·Margot Den HondtSydney Ch'ng
Jul 8, 2020·Journal of the National Comprehensive Cancer Network : JNCCN·David G PfisterSusan D Darlow

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.