Primary and Secondary Fibromyalgia Are The Same: The Universality of Polysymptomatic Distress

The Journal of Rheumatology
Frederick WolfeWinfried Häuser

Abstract

Polysymptomatic distress (PSD) is the underlying metric of fibromyalgia (FM), and levels of PSD can identify criteria-positive FM with > 90% accuracy. We used levels of the PSD scale to test whether symptom levels in primary FM (PFM) and secondary FM (SFM) were the same and whether symptoms were equivalent in persons not meeting FM criteria. We studied 1525 patients with a clinical diagnosis of FM and 12,037 patients with rheumatoid arthritis (RA). We used regression models to compare patients with potential and actual PFM to RA patients with potential and actual SFM for 17 key clinical variables. When controlled for PSD values, the widespread pain index, symptom severity scale, and pain, global, quality of life, and physical and mental component scores were essentially the same or only slightly different in PFM and SFM. Health Assessment Questionnaire-Disability Index scores were slightly higher in SFM (0.21 units), as was the painful joint count (1.6 joints). Overall, higher PSD scores were associated with more severe symptoms or abnormal status. PSD scores in patients not satisfying FM criteria and in patients satisfying criteria operated similarly. PFM and SFM are equivalent regarding symptom burden. PSD scores are more inf...Continue Reading

References

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Dec 6, 2016·Seminars in Arthritis and Rheumatism·Frederick WolfeBrian Walitt

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Citations

Jan 24, 2019·Expert Review of Clinical Immunology·Manfred Harth, Warren R Nielson
Feb 3, 2019·The Journal of Rheumatology·Robert M Bennett, Ronald Friend
Aug 5, 2019·Rheumatology International·Nada Mahmoud ShresherMohsen Hassan Elshahaly
Sep 22, 2018·Clinical Rheumatology·Manuel Martínez-Lavín
Oct 30, 2020·International Journal of Molecular Sciences·Massimo E Maffei
Apr 14, 2020·Reumatología clinica·Diego Felipe García Rodríguez, Carlos Abud Mendoza
Mar 31, 2021·Rheumatic Diseases Clinics of North America·Priyanka Iyer, Yvonne C Lee
Jul 13, 2021·Rheumatology International·Harish KancharlaAman Sharma
Aug 20, 2021·BMC Musculoskeletal Disorders·Michel KluteAxel Schäfer

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