PMID: 1201529Nov 1, 1975Paper

Primary and "transfer" seizure development in the kindled rat

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
W M Burnham

Abstract

An investigation was made of both primary and "transfer" kindling as they occur in ipsilateral limbic sites. Primary kindling was found to involve progressive growth of afterdischarge (AD), propagation and convulsive behavior. It was noted that AD growth did not take place gradually but occurred in sudden, large increments. "Transfer" (a significant acceleration of secondary kindling) was found at every secondary limbic site. It was associated with the early appearance of full-blown AD's, super-normal propagation, and well-developed seizures. The post-transfer interference of primary site function previously reported by Goddard et al was also found, but it occurred in significant amounts only after transfer kindling of the amygdala. It is believed that the data offer some support for both of the hypothetical mechanisms of transfer which have been proposed.

References

Nov 1, 1975·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·R Adamec
Nov 1, 1975·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·D C McIntyre
Mar 1, 1972·Electroencephalography and Clinical Neurophysiology·R J Racine
Mar 1, 1972·Electroencephalography and Clinical Neurophysiology·R J Racine
Nov 1, 1973·Electroencephalography and Clinical Neurophysiology·R J RacineJ G Gartner
Nov 1, 1973·Electroencephalography and Clinical Neurophysiology·D C McIntyre, G V Goddard
Nov 27, 1972·Brain Research·R J RacineW M Burnham
Nov 1, 1969·Experimental Neurology·G V GoddardC K Leech
May 1, 1964·Electroencephalography and Clinical Neurophysiology·R ELUL

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Citations

Apr 18, 2002·Brain Pathology·Douglas A CoulterWolfgang Löscher
May 8, 2008·The Journal of Comparative Neurology·Khushdev K ThindPaul S Buckmaster
Sep 2, 2009·Arquivos de neuro-psiquiatria·Joacir Graciolli CordeiroAndreas Schulze-Bonhage
Apr 1, 1982·Annals of Neurology·R M Dasheiff, J O McNamara
May 1, 2001·The European Journal of Neuroscience·P MohapelM E Corcoran
May 2, 2003·Annals of the New York Academy of Sciences·Michael A RogawskiHe Lia
Sep 22, 2000·Epilepsia·P MohapelM E Corcoran
May 28, 2008·Epilepsia·Dan C McIntyre, Krista L Gilby
Mar 4, 2010·Epilepsia·Brian W ScottW McIntyre Burnham
Dec 28, 1999·Epilepsia·E S Krishnamoorthy, M R Trimble
Nov 1, 1977·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·R RacineW M Burnham
Jan 1, 1981·Progress in Neuro-psychopharmacology·W M BurnhamK G Lloyd

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