Abstract
We report the MRI features in a series of four patients with primary angiitis of the central nervous system (PACNS). Based on MRI features, clinical presentation, paraclinical investigations and laboratory tests, including cerebrospinal fluid (CSF) analysis, various differentials were considered. In two patients with MRI findings of cortical, subcortical and deep white matter lesions, lack of mass effect, focal areas of bleed and heterogeneous parenchymal, leptomeningeal or pial enhancement and a normal magnetic resonance angiography, a differential diagnosis of primary angiitis of the CNS was also considered. In all patients, an open brain biopsy was advised to establish a definitive diagnosis of PACNS. Here, we briefly discuss the MRI features, correlation with clinical presentation and paraclinical parameters for the diagnosis of this entity. We also briefly review the literature.
References
Aug 1, 1979·Journal of Computer Assisted Tomography·A ValavanisJ Hayek
Jan 1, 1992·Radiology·T J GreenanH I Goldberg
Feb 1, 1992·Human Pathology·J T Lie
Sep 15, 1991·Cancer·D J InwardsT M Habermann
Jan 1, 1989·Surgical Neurology·M JohnsonR Collins
Sep 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·E H Koo, E W Massey
Feb 1, 1989·Neurology·P M Moore
May 1, 1988·Archives of Neurology·D S YoungerL P Rowland
Jul 1, 1994·Neurology·M Alhalabi, P M Moore
Jan 1, 1996·Neurology·N B Fountain, D A Eberhard
Jul 1, 1997·Arthritis and Rheumatism·L H CalabreseJ T Lie
Dec 31, 1997·Neurology·P F FinelliD F Uphoff
Jan 7, 1998·Journal of Neurosurgery·M NishikawaS Nishimura
Jun 2, 2000·Neurosurgery·C L RosenA Morita
Sep 8, 2001·Neuroradiology·A CampiM R Terreni
Citations
Jun 17, 2009·Neuroradiology·Youkyung LeeKee-Hyun Chang
Nov 21, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Zhao YinAiwu Zhang
Mar 5, 2005·European Neurology·Antonia CeccarelliIsabella Laura Simone
Sep 16, 2005·BMC Neurology·Carsten LukasChristian Börnke
Nov 4, 2009·Journal of Postgraduate Medicine·T FrancoL D McCullough
Mar 23, 2010·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·J A KinsellaS Whyte
Jun 6, 2009·Journal of the Neurological Sciences·Carlo Maria Rossi, Gabriele Di Comite
Apr 25, 2015·Neurologic Clinics·William J Powers
May 26, 2006·Neurosurgery·Boby V MaramattomNorbert G Campeau
Aug 30, 2008·Multiple Sclerosis : Clinical and Laboratory Research·M AriasF Vázquez
Nov 8, 2013·The Neurohospitalist·Yana L KrisemanS Andrew Josephson
Mar 24, 2017·Stroke; a Journal of Cerebral Circulation·Grégoire BoulouisUNKNOWN French Vasculitis Group
Jun 3, 2017·Neurosurgery·Otto Rapalino, Mark E Mullins
Jul 5, 2017·Experimental and Therapeutic Medicine·Lei NiuFeng Wang
Jun 1, 2005·Journal of Neuro-oncology·Martin BegemannLisa M Deangelis
May 19, 2017·Brain Tumor Research and Treatment·Joo-Seok LeeSeul-Kee Kim
Mar 8, 2008·CNS Spectrums·Carlo G Carandang, Allison L Grant