Primary B Cell Lymphoma of the CNS Mimicking Anti-LGI1 Limbic Encephalitis

Frontiers in Neurology
Christian ThomasNico Melzer

Abstract

Limbic encephalitis is a potentially paraneoplastic type of encephalitis mainly involving the limbic system. Recently, diagnostic criteria comprising clinical presentation as well as imaging, laboratory and electrophysiological findings have been established. Here, we show that incipient primary central nervous system lymphoma can closely resemble limbic encephalitis including positive testing for anti-LGI1 antibodies illustrating the need for thorough interpretation of initial laboratory and radiologic findings and tight follow-up examinations.

References

Mar 19, 2011·Annals of Neurology·Sarosh R IraniAngela Vincent
Oct 16, 2015·Neurology. Neuroimmunology and Neuroinflammation·Eoin P FlanaganSean J Pittock
Feb 26, 2016·Lancet Neurology·Francesc GrausJosep Dalmau
Oct 28, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C G BienT W May
Dec 14, 2016·Neurology. Neuroimmunology and Neuroinflammation·Ramona MiskeNico Melzer
Nov 22, 2017·Annals of Clinical and Translational Neurology·Manish MalviyaNorbert Goebels

❮ Previous
Next ❯

Citations

Sep 30, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Eleonora RigoniMatteo Gastaldi

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Related Feeds

CNS Lymphoma

In CNS lymphoma, cancerous cells from lymph tissues or other parts of the body form tumors in the brain and/or spinal cord. Here is the latest research on this rare non-Hodgkin lymphoma.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Related Papers

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Senthil RajappaMahendra Parage
Ryōikibetsu shōkōgun shirīzu
M Asahina, Takamichi Hattori
Nihon rinsho. Japanese journal of clinical medicine
Masahiro MoriTakamichi Hattori
© 2022 Meta ULC. All rights reserved