PMID: 11914139Mar 27, 2002Paper

Primary biliary cirrhosis and autoimmune cholangitis are not associated with coeliac disease in Crete

BMC Gastroenterology
Costantinos ChatzicostasElias Kouroumalis

Abstract

An increased prevalence of coeliac disease in patients with primary biliary cirrhosis has been recently reported. However, in other studies the association has not been confirmed. There have been no formal attempts to systematically evaluate patients with autoimmune cholangitis for coeliac disease. Sera from 62 patients with primary biliary cirrhosis, 17 with autoimmune cholangitis and 100 blood donors were screened for anti-gliadin, anti-endomysial, anti-reticulin, and IgA class antibodies to guinea pig liver-derived tissue transglutaminase. Eighteen untreated coeliacs served as methodological controls. Analyses were performed by using the chi2 and Fischer's exact tests. Anti-gliadin antibodies were detected in 21% of patients with primary biliary cirrhosis, 35% of patients with autoimmune cholangitis, and 3% of controls (p < 0.001). IgA class gliadin antibodies positivity was more pronounced in patients with Scheuer's stage III-IV disease (p < 0.05). Anti-transglutaminase antibodies were detected in 10% and in 18% of patients with primary biliary cirrhosis and autoimmune cholangitis respectively (p < 0.001). Anti-reticulin and anti-endomysial antibodies were negative in all patients. Duodenal biopsies were performed in 59% an...Continue Reading

References

Aug 1, 1982·Scandinavian Journal of Gastroenterology·R OlssonL Rydberg
Jun 1, 1995·Baillière's Clinical Gastroenterology·M Mäki
Jul 1, 1994·Scandinavian Journal of Gastroenterology·S LindgrenS Eriksson
Apr 1, 1997·Gut·J Heathcote
Jun 14, 1997·Lancet·M Mäki, P Collin
Jul 1, 1997·Journal of Clinical Gastroenterology·W DickeyM E Callender
Dec 3, 1998·Gastroenterology·W DieterichD Schuppan
Aug 13, 1999·The American Journal of Gastroenterology·F BiagiP J Ciclitira
Sep 4, 1999·Journal of Clinical Pathology·R J LockD J Unsworth
Sep 1, 2000·Gastrointestinal Endoscopy·T Rokkas, A Karameris
Feb 24, 2001·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·D P Jewell

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Citations

Aug 2, 2008·Alimentary Pharmacology & Therapeutics·M L HainesP R Gibson
Sep 9, 2006·Journal of Clinical Laboratory Analysis·N BizzaroE Tonutti
Feb 11, 2005·Current Opinion in Gastroenterology·Michael Trauner, James L Boyer
Oct 31, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Alberto Rubio-Tapia, Joseph A Murray
Aug 12, 2005·European Journal of Gastroenterology & Hepatology·Barbara SchmidtPeter Ferenci
Aug 9, 2005·Clinical and Diagnostic Laboratory Immunology·Anastasios E GermenisGeorgios N Dalekos
Aug 12, 2015·World Journal of Gastrointestinal Pharmacology and Therapeutics·Elias Kouroumalis, George Notas
Feb 23, 2017·World Journal of Gastroenterology : WJG·Janaína Luz Narciso-Schiavon, Leonardo Lucca Schiavon
Feb 20, 2021·Journal of Clinical and Translational Hepatology·Jaimy Villavicencio Kim, George Y Wu
May 24, 2008·Gastroenterology Clinics of North America·Susan H Barton, Joseph A Murray

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