Primary biliary cirrhosis, sicca complex, and dysphagia

Dysphagia
F W MangJ Heathcote

Abstract

We investigated symptoms suggestive of swallowing problems in patients with primary biliary cirrhosis, some of whom displayed features of sicca complex. A prospective study of 95 consecutive patients with primary biliary cirrhosis was conducted at a single teaching hospital using a questionnaire administered over the telephone. Some symptoms of sicca complex (dry mouth and/or dry eyes) were found in 65 patients (68.4%). Subjective xerostomia alone was present in 45 patients (47.4%). The questionnaire revealed an increase in incidence of dysphagia in xerostomia subjects, affecting 21 of 45 patients, compared with 6 of 50 non-xerostomia patients. Multivariate logistic regression analysis showed that confounding factors such as age, obesity, cigarette smoking, and medications associated with a dry mouth could not explain these findings. Twenty-eight patients complained of hoarseness, 23 of coughing, and 14 of wheezing, all of which were significantly more frequent than in the 50 patients without xerostomia. Heartburn affected 17 xerostomia patients and 15 non-xerostomia patients, indicating no difference in frequency between these two groups, even after age, obesity, cigarette smoking, and medications associated with heartburn wer...Continue Reading

Citations

Mar 25, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·E J Heathcote
Mar 15, 2001·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·P C FoxJ M Cummins
Dec 10, 2002·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Philip C FoxJoseph M Cummins
Jul 16, 2009·Seminars in Immunopathology·Simon HohenesterUlrich Beuers
Nov 3, 2015·Expert Review of Gastroenterology & Hepatology·Ahmad H AliKeith D Lindor
Jul 24, 2013·Clinics and Research in Hepatology and Gastroenterology·Rodrigo LiberalDimitrios P Bogdanos
May 16, 2009·Clinics in Liver Disease·Karen L Krok, Santiago J Munoz
Mar 24, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Inger von BültzingslöwenMorten Schiødt
Jun 26, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Keith D LindorUNKNOWN American Association for Study of Liver Diseases
Aug 7, 2009·Oral Diseases·L M KasmanM J Pilgrim
Sep 12, 2008·Liver International : Official Journal of the International Association for the Study of the Liver·Gideon M HirschfieldE Jenny Heathcote
Nov 23, 2012·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Jaana Helenius-HietalaJukka H Meurman
Dec 3, 2014·Archives of Oral Biology·Jamil SalehFernanda Gonçalves Salum
Mar 16, 2017·Gut and Liver·Sara L ChalifouxSammy Saab
Aug 12, 2015·World Journal of Gastrointestinal Pharmacology and Therapeutics·Elias Kouroumalis, George Notas
Nov 1, 2018·Acta Clinica Belgica·Mahdieh-Sadat Moosavi, Hoda Barati

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved