Primary cardiac lymphoma: diagnostic tools and treatment challenges.

Irish Journal of Medical Science
R BamburyD Fennelly

Abstract

Primary cardiac lymphoma (PCL) is a rare malignancy and the optimal treatment strategy remains uncertain. It appears to respond much better to systemic chemotherapy than to surgery and it should be considered in the differential diagnosis of all cardiac tumours before definitive management is undertaken. We report a case of this rare disorder treated successfully with a combination of rituximab and cyclophosphamide, adriamycin, vincristine and prednisolone. The patient developed recurrent unstable ventricular tachycardia (VT) post-chemotherapy secondary to extensive scarring at the tumour site. The tumour as well as the post-treatment scarring is well illustrated by cardiac magnetic resonance imaging highlighting its usefulness in this setting. An implantable cardioverter defibrillator (ICD) was placed. This is only the second case in the literature of PCL to have an ICD placed for recurrent VT. A brief literature review is included.

References

Dec 6, 2001·Leukemia Research·Giovanni RollaFederico Caligaris-Cappio
Nov 26, 2002·Virchows Archiv : an International Journal of Pathology·Lara ChalabreysseFrançoise Thivolet-Bejui
May 14, 2003·Journal of the American College of Cardiology·James C C MoonDudley J Pennell

❮ Previous
Next ❯

Citations

Oct 26, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Shan-Hui HuangYen-Bin Liu
Mar 21, 2018·Current Treatment Options in Cardiovascular Medicine·Nicolas PalaskasJuan C Lopez-Mattei
Sep 7, 2018·Leukemia & Lymphoma·Natalia Cichowska-CwalińskaRenata Zaucha
May 24, 2014·Chonnam Medical Journal·Yong JeoungSang Yoon Chung
Jan 6, 2017·Case Reports in Cardiology·Baljit SinghTarik Hadid
Aug 29, 2021·Trends in Cardiovascular Medicine·Sanaz AsadianMohammad Mehdi Hemmati Komasi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.