Primary central nervous system plasmablastic lymphoma presenting in human immunodeficiency virus-negative but Epstein-Barr virus-positive patient: a case report.

Diagnostic Pathology
Li Ying ZhangZhi Yong Liang

Abstract

We report a 32-year-old Outer Mongolian man, with plasmablastic lymphoma (PBL) primarily occured in the central nervous system and diagnosed by surgical resection. This patient appeared headache and magnetic resonance imaging (MRI) showed multiple lesions in the right cerebral hemisphere including the right frontal-parietal lobe and right basal ganglia and the left cerebellum, he was diagnosed as lymphoma by stereotactic biopsy in January 2009 in local hospital, and was given radiotherapy 33 times after the biopsy. The patient was admitted to The Military General Hospital of Beijing PLA., Beijing, P.R. China on March 9th, 2011, with chief complaints of right limbs convulsioned suddenly, then fell down and lose of his consciousness, then awoke after 4 to 5 minutes, with symptoms of angulus oris numbness and the right upper limb powerless ten days ago.MRI of the brain revealed a well-defined hyperdense and enhancing mass in the left frontal-parietal lobe, the meninges are closely related, there was extensive peritumoural edema noted with pressure effects, as evident by effacement of the left lateral ventricles and a 0.5 cm shift of the midline to the right side.Surgical resection showed markedly atypical, large singly dispersed o...Continue Reading

References

Jul 27, 2004·Cerebrovascular Diseases·Hanne Christensen, Gudrun Boysen
Nov 7, 2007·Neuropathology and Applied Neurobiology·S ShuangshotiP S Thorner
Mar 21, 2008·The Lancet Infectious Diseases·David J RiedelBruce L Gilliam
Sep 14, 2010·Diagnostic Pathology·Tereza C CardosoAdriana Hc Nogueira
Oct 22, 2010·The American Journal of Surgical Pathology·Alexandra ValeraElías Campo

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Citations

Mar 22, 2014·Diagnostic Pathology·Noémi EszesVeronika Müller
Dec 21, 2013·Pathology, Research and Practice·Tiantian ZhangQiongli Zhai
Apr 4, 2013·Expert Review of Hematology·Mahmoud Rezk Abdelwahed Hussein
Mar 16, 2019·BMJ Case Reports·Ruben RhoadesOnder Alpdogan
Aug 11, 2015·Applied Immunohistochemistry & Molecular Morphology : AIMM·Antonio D'AntonioFilippo Fraggetta

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Methods Mentioned

BETA
biopsy
PCR

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