Primary Cutaneous Acral CD8(+) T-Cell Lymphoma

Archives of Pathology & Laboratory Medicine
Vivian M HathucLauren B Smith

Abstract

Primary cutaneous acral CD8(+) T-cell lymphoma is a new provisional entity in the 2016 revision of the World Health Organization classification of lymphoid neoplasms. This is a challenging diagnosis because of its rarity, as well as its morphologic and immunophenotypic overlap with other CD8(+) cytotoxic lymphoid proliferations. Appropriate classification of this entity is crucial because of its indolent clinical behavior compared with other CD8(+) T-cell lymphomas. Knowledge of the clinical setting, sites of involvement, and morphologic features can aid in correct diagnosis. Here, we review the clinical and pathologic features of primary cutaneous acral CD8(+) T-cell lymphoma with an emphasis on the differential diagnosis among other C8(+) T-cell lymphomas.

References

Sep 1, 1986·Journal of the American Academy of Dermatology·G S WoodR A Warnke
Jun 18, 2002·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Filiz SenL Jeffrey Medeiros
Feb 5, 2005·Blood·Rein WillemzeChris J L M Meijer
Jan 18, 2006·Journal of Cutaneous Pathology·Rein Willemze, Chris J L M Meijer
Nov 29, 2007·The American Journal of Surgical Pathology·Tony PetrellaFlorent Grange
Feb 2, 2010·Journal of the American Academy of Dermatology·Ya-Jing HsuCheng-Hsiang Hsiao
Nov 19, 2010·Journal of Cutaneous Pathology·Brian L SwickVincent Liu
May 22, 2013·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Seo In JeongHeoung Keun Kang
Oct 1, 2014·Archives of Pathology & Laboratory Medicine·Thanh T Ha LanAlexandra C Hristov

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Citations

May 10, 2018·International Journal of Laboratory Hematology·E Matutes
Jun 20, 2018·Frontiers in Oncology·Kazuyasu Fujii
Dec 16, 2018·Journal of Cutaneous Pathology·Ferdinand TobererLorenzo Cerroni
Jul 18, 2020·The American Journal of Dermatopathology·Lucia Prieto-TorresSocorro María Rodríguez-Pinilla
Mar 21, 2021·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Daniel C MorseMadeleine Duvic
Jul 20, 2021·The American Journal of Dermatopathology·Joshua R RaviczAlejandro A Gru
Aug 28, 2021·Nature Reviews. Disease Primers·Reinhard DummerEgle Ramelyte

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