Primary Cutaneous CD30-Positive Large T-Cell Lymphoma in an 80-Year-Old Man: A Case Report.

ISRN Dermatology
Rehan Hussain, Amir Bajoghli

Abstract

Primary cutaneous CD30-positive large cell lymphoma (CD30+ PCLCL) is a rare subtype of cutaneous T-cell lymphoma (CTCL) that can present in a variety of ways. We report a patient with a three-month history of an enlarging, exophytic mass with two smaller satellite lesions on the left forearm. Biopsy of the skin stained positive for CD30, and, after thorough systemic evaluation, a diagnosis of CD30+ PCLCL was made. When PCLCL is suspected, it is important to perform immunohistological studies for CD30 types and conduct a thorough workup to rule out systemic LCL. These measures will reduce the use of unnecessarily aggressive chemotherapy regimens for CD30+ PCLCL, an indolent disease with a favorable prognosis.

References

Jun 1, 1993·Journal of Cutaneous Pathology·J KrishnanG F Kao
Nov 1, 1993·Journal of the American Academy of Dermatology·C CamisaR Tuthill
Feb 28, 2002·Journal of the American Academy of Dermatology·Maxwell A FungJane M Grant-Kels
Jan 9, 2004·Hematology/oncology Clinics of North America·Rein Willemze, Chris J L M Meijer

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Citations

Jun 26, 2015·Science Translational Medicine·Zainul S HasanaliElliot M Epner

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Methods Mentioned

BETA
biopsy
X-ray

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