PMID: 2499111Jan 1, 1989Paper

Primary duodenal carcinoma arising in a non-vaterian tubulo-villous adenoma. A case report with immunocytochemical analysis and review of the literature

Virchows Archiv. A, Pathological Anatomy and Histopathology
H R ZenklusenM Oberholzer

Abstract

Primary duodenal carcinoma and duodenal adenoma are rare tumours. Duodenal carcinoma makes up about 0.3% of all malignant tumours of the gastrointestinal tract (Alwmark et al. 1980; Spira et al. 1977). The present paper describes a duodenal carcinoma arising in a mixed tubulo-villous non-Vaterian adenoma in a 68 year old male. Immunocytochemical analysis revealed evidence of neuroendocrine differentiation in both adenoma and carcinoma. In a review of the literature a correlation between the size of adenoma and the probability of concomitant carcinoma is demonstrated. Duodenal adenoma measuring more than 4 cm in diameter should be considered potentially malignant.

References

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Citations

Jan 1, 1992·Surgery Today·Y KojimaY Imamura
Dec 12, 2012·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Xiang-Yuan WuXiang-Bo Wan
Jan 23, 1999·Journal of Clinical Gastroenterology·Y TanakaY Esaki
Jun 1, 1995·Postgraduate Medical Journal·O A AdedejiM Garcia-Zarco
Aug 22, 2009·AJR. American Journal of Roentgenology·Giovanni MaconiGabriele Bianchi Porro
Jun 20, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Jie ChenXiang-Yuan Wu

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