Primary Epidermoid Cyst of Biliary Duct Presenting as Choledochal Cyst

International Journal of Surgical Pathology
Dong Hyang KwonMetin Ozdemirli

Abstract

Choledochal cyst is a cystic dilation of the biliary tree that can increase the risk of malignancy in bile ducts and the gallbladder. These are usually lined by bile duct epithelium, which may undergo intestinal and squamous metaplasia. This is the first report of clinically diagnosed type II choledochal cyst that is entirely lined by metaplastic stratified squamous epithelium, unlike most other cysts, which are histologically lined by bile duct epithelium. This observation can potentially explain the underlying pathogenic mechanism of rare reports of squamous cell carcinomas arising in bile duct systems.

References

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Citations

Nov 17, 2020·European Journal of Pediatric Surgery Reports·Helena Reusens, Mark Davenport
May 31, 2019·Case Reports in Gastroenterology·Anneke Ten HoveJoost M Klaase

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Methods Mentioned

BETA
exome sequencing

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Carcinoma, Squamous Cell

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