Primary extranodal non-Hodgkin's lymphoma of the vagina: a case report and a review of the literature

Acta Haematologica
Salvatore GuastafierroUmberto Falcone

Abstract

Primary lymphoma of the female genital tract is very rare. We report the case of a 36-year-old woman who was referred to our hospital because of an indeterminate Pap smear test. The colposcopy showed a thickening of the posterior vaginal wall and various irregular ulcerated nodular lesions. Histological examination, immunohistochemistry and the staging procedures were conclusive of diffuse large B-cell lymphoma of the vagina, stage IEA. Complete remission was achieved after 6 cycles of immunopolychemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). No relapse has occurred during a follow-up of 71 months. Moreover, we reviewed the 62 previously reported cases of primary extranodal non-Hodgkin's lymphoma of the vagina, focusing on clinicopathological and therapeutic aspects, to better characterize this unusual disease.

Citations

Apr 3, 2018·Case Reports in Obstetrics and Gynecology·Lilian Yukari MiuraWilliam Kondo
Mar 21, 2018·Oncology Letters·Feng WangZheng Fu
May 8, 2019·BMJ Case Reports·Nanak BhagatSanjaya Kalkur

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Related Papers

The American Journal of the Medical Sciences
Salvatore GuastafierroGiuseppe Colella
Annals of Hematology
Aylin Fidan KorcumGulgun Erdogan
Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology
Samrat DuttaKakoli Choudhury
© 2021 Meta ULC. All rights reserved