Primary Fascial Closure During Laparoscopic Ventral Hernia Repair Improves Patient Quality of Life: A Multicenter, Blinded Randomized Controlled Trial.

Annals of Surgery
Karla BernardiMike K Liang

Abstract

Observational studies have reported conflicting results with primary fascial closure (PFC) versus bridged repair during laparoscopic ventral hernia repair (LVHR). The aim of the study was to determine whether when evaluated in a randomized controlled trial (RCT), PFC compared to bridged repair would improve patient quality of life (QoL). In this blinded, multicenter RCT, patients scheduled for elective LVHR (hernia defects 3 to 10 cm on computed tomography scan) were randomized to PFC versus bridged repair. Primary outcome was change in QoL after LVHR using a validated, hernia-specific survey (1 = poor QoL and 100 = perfect QoL) that measures pain, function, cosmesis, and satisfaction. Secondary outcomes were postoperative surgical site occurrences (including hematoma, seroma, surgical site infection, and wound dehiscence), abdominal eventration, and hernia recurrence. The trial was powered to detect a difference in change in QoL of 7 points between the study groups. Outcomes were compared with Mann-Whitney U test or chi-square. A total of 129 patients underwent LVHR and 107 (83%) completed follow-up at 2 years. Patients from both groups were similar at baseline. On median follow-up of 24 months (range: 9-42), patients treated ...Continue Reading

References

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Citations

Dec 27, 2019·JAMA Surgery·Karla BernardiMike K Liang
Jan 24, 2020·The British Journal of Surgery·M W ChristoffersenT Bisgaard
Jan 14, 2020·Hernia : the Journal of Hernias and Abdominal Wall Surgery·S J ZolinD M Krpata
Jul 16, 2020·BMJ : British Medical Journal·Oscar A OlavarriaMike K Liang
Apr 14, 2020·Journal of Surgical Case Reports·Elroy P Weledji, Theophile C Nana
Oct 29, 2020·Journal of Robotic Surgery·James J Butz, Seth L Newman
Apr 28, 2020·The British Journal of Surgery
Apr 11, 2021·Hernia : the Journal of Hernias and Abdominal Wall Surgery·F KöckerlingD Weyhe
Dec 16, 2020·Surgery·Hailie CiomperlikMike K Liang
Sep 25, 2021·Hernia : the Journal of Hernias and Abdominal Wall Surgery·F AliG Wallin

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