PMID: 6171335Dec 15, 1981Paper

Primary gastric choriocarcinoma: immunohistochemistry, postmortem documentation, and hormonal effects in a postmenopausal female

Cancer
J Wurzel, J J Brooks

Abstract

A rare tumor, primary choriocarcinoma of the stomach, occurred in a post menopausal female. The diagnosis was confirmed by autopsy and by immunohistochemical demonstration of HCG in trophoblastic tumor cells. Theories concerning development of this neoplasm are briefly discussed. In addition, this postmenopausal case uniquely permitted examination of the hormonal effects of the tumor on target tissues without the clouding issue of normal menstrual hormones. It appears that the observed estrogen- and progesterone-related tissue responses were not mediated through the ovary; instead, direct tumor production of these hormones is implicated.

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Citations

Jun 1, 1996·Journal of Gastroenterology·M TokisueR Morita
Jan 27, 2005·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·C A R LokJ van der Velden
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Jul 29, 2015·International Journal of Surgery Case Reports·Vilma Florença MartinsJorge Santos
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Dec 9, 2010·Rare Tumors·Elena MagniMaria Giulia Zampino
Jul 29, 2000·Journal of Clinical Gastroenterology·L WangS W French
Dec 12, 2001·Archives of Pathology & Laboratory Medicine·Z LiuJ C Cruz-Caudillo
Jan 2, 2008·Gastroentérologie Clinique Et Biologique·Guillaume Granier, Christiane Marty-Double

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