Primary Gastric Lymphoma, Epidemiology, Clinical Diagnosis, and Treatment

Cancer Control : Journal of the Moffitt Cancer Center
Luis Miguel Juárez-SalcedoSamir Dalia

Abstract

Primary gastric lymphoma (PGL) is the most common extranodal non-Hodgkin lymphoma and represents a wide spectrum of disease, ranging from indolent low-grade marginal zone lymphoma or mucosa-associated lymphoid tissue (MALT) lymphoma to aggressive diffuse large B-cell lymphoma. The PGL is a relatively rare cancer and easily misdiagnosed due to its unspecific symptoms of the digestive tract. The medical literature and ongoing clinical trials were reviewed on the clinical presentation, diagnosis, prognosis, prevention, and treatment of PGL. Primary gastric lymphoma is an event in the course of cancer with a variable clinical presentation and a wide differential diagnosis. Chronic gastritis secondary to Helicobacter pylori ( H pylori) infection has been considered a major predisposing factor for MALT lymphoma. Magnetic resonance imaging and endoscopic ultrasonography have helped in staging of these cancers. The clinical course and prognosis of this disease are dependent on histopathological subtype and stage at the time of diagnosis. A global therapeutic approach to the cure of PGL has completely changed over the past 10 years, including innovative and conservative options to reduce treatment toxicity. Due to the rarity of PGL, man...Continue Reading

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Citations

Oct 27, 2018·Journal of Medicine and Life·Petruta Violeta FilipCorina Silvia Pop
Aug 19, 2020·Journal of Gastrointestinal Cancer·Paramita GhoshNabendu Murmu
Jul 2, 2019·The American Journal of Surgical Pathology·Jennifer Y JuNadine S Aguilera
Aug 1, 2020·The British Journal of Ophthalmology·Frederik HolmSteffen Heegaard
Nov 11, 2019·Abdominal Radiology·Abdelrahman K HanafyKhaled M Elsayes
May 23, 2020·Clinical and Experimental Gastroenterology·Lina ElsalemOsama Aloudat
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Dec 29, 2020·Indian Journal of Surgical Oncology·Fabio CarboniMario Valle
Jan 12, 2021·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Maria Eduarda CoutoJosé Mariz
Mar 18, 2021·Seminars in Diagnostic Pathology·Jennifer Y JuElizabeth L Courville
Jun 9, 2021·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Vivian Petersen WagnerManoela Domingues Martins
Aug 25, 2021·Clinical and Experimental Medicine·Zhengzi QianHaifeng Zhao
Apr 10, 2021·Archives of Pathology & Laboratory Medicine·Jessica Alvarez-LesmesJulio Poveda

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Methods Mentioned

BETA
biopsy
biopsies
PCR
surgical resection

Software Mentioned

GELA

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