Primary Gougerot-Sjögren syndrome: a dermatological approach

Journal of the European Academy of Dermatology and Venereology : JEADV
A-M RoguedasL Misery

Abstract

Gougerot-Sjögren syndrome (GSS) is a chronic heterogeneous non-organ-specific autoimmune disease, encompassing a wide spectrum of clinical manifestations. It is characterized by a lymphocytic infiltration of the exocrine glands, also called epitheliitis, resulting in xerostomia and keratoconjunctivitis sicca. The skin can also be involved; for example, xerosis is a consequence of epitheliitis. Dermatological consequences of polyclonal reactivity are vasculitis and manifestations of B-cell proliferation vary from plasma cell infiltrates to B-cell lymphoma.

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Citations

Apr 6, 2013·BMC Medicine·Andreas Kronbichler, Gert Mayer
Mar 19, 2014·Annales de dermatologie et de vénéréologie·N KlugerL Misery
Jun 2, 2016·European Respiratory Review : an Official Journal of the European Respiratory Society·Thomas FlamentSylvain Marchand-Adam
Feb 23, 2021·Joint, Bone, Spine : Revue Du Rhumatisme·Camille VillonAlain Saraux

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