Primary gynecological neoplasms and clinical outcomes in patients diagnosed with breast carcinoma

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
P F EscobarJoseph P Crowe

Abstract

The purpose of this study was to quantify and describe nonmammary neoplasms (n-MN), particularly gynecological neoplasms, in a patient population previously diagnosed with breast cancer. Data were collected prospectively in our institutional review board-approved registry for patients diagnosed with infiltrating breast cancer or ductal carcinoma in situ. Patients who developed a second, n-MN were identified; neoplastic site, time to development after breast cancer, and clinical outcomes were recorded. FIGO stage was recorded for patients who developed a gynecological neoplasm. Synchronous bilateral breast cancer was defined as a second, contralateral diagnosis made within 12 months of the first and, similarly, synchronous n-MN were defined as those identified within 1 year of a breast cancer diagnosis. Outcome curves were generated using the method of Kaplan and Meier, and compared using the log-rank test. Of 4126 patients diagnosed with breast cancer, 3% developed a n-MN, the majority of which were nongynecological and asynchronous to the initial breast cancer diagnosis. Three percent of patients diagnosed with breast cancer were diagnosed with a second, n-MN. Among patients who developed a n-MN, most developed a nongynecologi...Continue Reading

References

Jul 1, 1984·Gynecologic Oncology·J H AxelrodJ G Boyce
Jan 1, 1993·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H BrennerH Ziegler
Nov 5, 1997·Cancer Causes & Control : CCC·N Volk, V Pompe-Kirn
Jan 1, 1995·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·T. TakedaR. Kudo
Feb 6, 2003·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Sep 4, 2003·Journal of the National Cancer Institute·Katherine Arnold
Apr 2, 2004·Expert Review of Anticancer Therapy·Emiel J Rutgers
Aug 5, 2004·Obstetrics and Gynecology·Brian M SlomovitzKaren H Lu

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Citations

Dec 23, 2006·Breast Cancer Research and Treatment·Amy Trentham-DietzJohn M Hampton
Jan 12, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Kefah MokbelTadaharu Matsunaga
Dec 11, 2007·Experimental Eye Research·Yoram CohenNitza Goldenberg-Cohen

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