PMID: 6538110Apr 15, 1984Paper

Primary hemangiosarcoma of the spleen with angioscintigraphic demonstration of metastases

Cancer
G G HermannE Hippe

Abstract

A case of primary hemangiosarcoma of the spleen in a 48-year-old woman is presented. Twenty-eight months after splenectomy the patient developed a severe anemia of the microangiopathic type, thrombocytopenia, and a leukoerythroblastic peripheral blood picture. In contrast to x-ray and conventional 99mTc-methylene-diphosphonate (MDP) bone scintigraphy, which showed only a few minor focal changes in the spine and ribs, angioscintigraphy with in vitro labeled 99mTc-erythrocytes revealed extensive pathologic accumulations throughout the spine, femurs, and the liver, indicating the presence of extremely vascular metastases. Autopsy 15 months later confirmed the scintigraphic findings. Angiography with 99mTc-labeled erythrocytes seems to be useful for monitoring metastases from hemangiosarcomas.

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Citations

Feb 5, 1999·Journal of Clinical Ultrasound : JCU·S AytaçI Erden
Jan 1, 1989·Urologic Radiology·M B DesaiR Weiner
Feb 23, 2010·Clinical & Experimental Metastasis·B JobkeJ Freyschmidt
Oct 20, 2000·La Revue de médecine interne·S Villedieu PoignantP Dupont
Jun 19, 2012·Toxicological Sciences : an Official Journal of the Society of Toxicology·Janani SaikumarVishal S Vaidya
Sep 1, 1985·The British Journal of Radiology·J M Wafula
Sep 1, 1985·The British Journal of Radiology·T SingcharoenH Baddeley
May 28, 2021·The Journal of International Medical Research·Xiaotong PengHuining Liu
Jun 24, 2021·Expert Review of Gastroenterology & Hepatology·Brian Lee Juin Hsien, Vishal Girishchandra Shelat

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