Primary hepatic diffuse large B-cell lymphoma: unusual presentation and imaging features

Current Problems in Diagnostic Radiology
Ekta DhamijaArun K Gupta

Abstract

Primary hepatic lymphoma is an uncommon malignancy affecting the liver, with limited reports and series in the literature. Imaging appearance is not well described, with no definite features suggesting a diagnosis, and it may mimic other focal hepatic lesions. However, biopsy is needed in most of the cases for confirmation. We report a case of 22-year-old pregnant woman who on ultrasonography showed a large heteroechoic solitary liver mass mimicking focal nodular hyperplasia. Further evaluation after parturition with contrast-enhanced magnetic resonance imaging showed a large mass with central scar and peripheral diffusion restriction and contrast enhancement, which was atypical. Biopsy confirmed it as lymphoma. The case illustrates unusual presentation and magnetic resonance imaging features, including diffusion-weighted imaging, of primary hepatic lymphoma in a young female.

References

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Apr 2, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jean-Pierre BronowickiEric Labouyrie
Aug 20, 2008·Journal of Medical Case Reports·Fyeza S HaiderSharif Khan
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Aug 22, 2009·Journal of Medical Imaging and Radiation Oncology·K M ElsayesJoel Platt
Mar 17, 2012·World Journal of Radiology·Ernst Ja StellerIzaak Q Molenaar
Sep 7, 2012·Journal of Medical Case Reports·Fatmir BilajGjergji Vreto

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Citations

Jun 20, 2015·Digestive Diseases and Sciences·Daniel CastresanaArchana Kaza
Aug 15, 2020·Clinical Journal of Gastroenterology·Kumi OzakiHirohiko Kimura
Apr 17, 2020·Journal of Cancer Research and Clinical Oncology·Davide IppolitoSandro Sironi
Feb 21, 2018·Abdominal Radiology·Stefano ColagrandeLuigi Grazioli

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