Primary hepatic neuroendocrine tumor with multiple liver metastases: A case report with review of the literature

World Journal of Gastroenterology : WJG
Kai YangJi-Xiang Guo

Abstract

We herein present a case involving a 41-year-old woman in whom ultrasound examination revealed multiple liver hemangiomas more than 3 years ago. Follow-up ultrasound examination revealed that the masses had significantly increased; the largest was located in the right lobe (about 8.2 cm × 7.4 cm × 6.0 cm). Abdominal multidetector computed tomography revealed multiple well-circumscribed, heterogeneous, hypodense masses (largest, 6.4 cm × 6.3 cm × 5.0 cm) with significant contrast enhancement during the arterial and portal phases and with contrast wash-out and peripheral enhancement during the delayed phases. Magnetic resonance images demonstrated multiple well-circumscribed, heterogeneous, hypointense hepatic masses with significant contrast enhancement (largest, 6.4 cm × 6.5 cm × 5.1 cm); multiple enlarged porta lymph nodes; and multiple slightly enlarged retroperitoneal lymph nodes. Histological and immunohistochemical examination of the right mass biopsy specimen suggested a malignant neoplasm that had originated from a neuroendocrine cell type (grade 2 well-differentiated neuroendocrine carcinoma). After performing a systemic examination to exclude metastasis from an extrahepatic primary site, we considered that the masses h...Continue Reading

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Citations

Oct 18, 2019·Annals of Surgical Treatment and Research·Jay JungYo-Han Park
Jun 11, 2016·Molecular and Clinical Oncology·Asahiro MorishitaTsutomu Masaki
Mar 21, 2017·Case Reports in Pathology·Mohd Elmugtaba IbrahimAziza Nassar
Jun 27, 2020·The Journal of International Medical Research·Yijun XiaLong Xia
Jul 3, 2018·World Journal of Gastroenterology : WJG·Xiang-Fei MengWei-Dong Duan
Oct 3, 2020·World Journal of Gastrointestinal Oncology·Hao-Hao WangXiao-Wei Dang
Mar 7, 2018·BMC Clinical Pathology·Zi-Ming ZhaoJeffrey P Townsend
Oct 1, 2020·Radiology Case Reports·Richa D JainSudhir Kale
Aug 31, 2021·Frontiers in Surgery·Murat Baki Yıldırımİlgin Özden

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