Primary High-Risk Human Papillomavirus Testing for Cervical Cancer Screening in the United States: Is It Time?

Archives of Pathology & Laboratory Medicine
Melina B Flanagan

Abstract

- The most recent update to cervical cancer screening guidelines offers interim guidance on the use of primary human papillomavirus (HPV) screening, with algorithms for management of results. After decades of screening with pure cytology and a shorter time with adjunctive HPV or cotesting with Papanicolaou (Pap) test and HPV, this is a significant change to our screening methods. - To briefly review the history of cervical cancer screening, the evidence upon which these interim guidelines were based, the arguments for and against primary HPV testing, and the current state of the field. - Primary studies, review articles, and commentaries were reviewed. - While there is evidence both for and against primary HPV testing, there are a growing number of countries adopting the practice. It would be worthwhile to be informed and prepared for such a change in the United States as well.

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Citations

May 23, 2019·Human Vaccines & Immunotherapeutics·Yan Geng, Liyan Liu
Feb 11, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Santhosh KuriakoseNurul Ameen
Oct 14, 2018·World Journal of Surgical Oncology·Li ZhuDihong Tang
Dec 18, 2020·Diagnostic Cytopathology·Ane Francyne CostaFabiana Botelho de Miranda Onofre
Nov 19, 2020·Journal of Oncology·Carlo A LiveraniAndrea Ciavattini
Jul 20, 2021·Current Problems in Cancer·Sevgi KocFulya Kayikcioglu

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