Primary hyperparathyroidism presenting as acute psychosis secondary to hypercalcaemia requiring curative parathyroidectomy

Journal of Surgical Case Reports
Prateush SinghJustin Shute

Abstract

Primary hyperparathyroidism (PHPT) can cause hypercalcaemia secondary to a pathologically high secretion of parathyroid hormone. Rarely this can first manifest as acute psychosis. It is imperative to exclude organic causes of psychosis before labelling the psychosis as primarily psychological. If hypercalcaemia is revealed, investigation is required to elucidate the underlying cause whilst instigating treatment to lower serum calcium levels. If PHPT is the underlying pathology, subsequent treatment involves surgical exploration and resection of the parathyroid adenoma or hyperplasia.

References

Jun 24, 2004·Primary Care Companion to the Journal of Clinical Psychiatry·Thomas W. Heinrich, Garth Grahm
Feb 25, 2006·Primary Care Companion to the Journal of Clinical Psychiatry·Ahsan MahmoodFatima H Hina
Jul 3, 2007·The Oncologist·James W Suliburk, Nancy D Perrier
Feb 5, 2013·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Shonni J SilverbergJohn P Bilezikian
Jul 20, 2013·Annals of General Psychiatry·Alice TangPeter Campbell

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Citations

Jan 23, 2020·AACE Clinical Case Reports·Camilla Maria Guimarães AugustoMarcos Oliveira Pires de Almeida

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