Primary Intracranial Leiomyosarcoma Secondary to Glioblastoma: Case Report and Literature Review.

Frontiers in Oncology
Liyan ZhaoYunqian Li

Abstract

Leiomyosarcoma is a highly malignant soft-tissue sarcoma with a poor prognosis. In recent years, treatment for leiomyosarcoma has not shown much progress. Primary intracranial leiomyosarcoma (PILMS) is a much rarer type of neoplasm, which occurs more frequently in immunocompromised patients. PILMS cases reported in the literature are scarce and treatment strategy and prognosis are still under debate. In this study, a case of PILMS secondary to the total resection of giant cell glioblastoma is reported. A 38-year-old male was hospitalized with a three-month history of a temporal opisthotic bump. His medical history included a total resection of a tumor located in the right temporal lobe performed 4 years earlier. Pathological examination led to a diagnosis of giant cell glioblastoma, and the patient underwent postoperative chemotherapy with temozolomide for 6 weeks plus simultaneous radiotherapy with 63.66 Gary. Four years later, during regular follow-up, a preoperative MRI brain scan resulted in a well-defined signal pointing out two nodule-like features located at the right temporal lobe and subcutaneous soft tissue, respectively, and near the area where the previous giant cell glioblastoma was located. The mass was completely...Continue Reading

References

May 1, 1991·Histopathology·W PaulusK Jellinger
Aug 1, 1989·Journal of Neurosurgery·D N LouisR G Ojemann
Feb 1, 1988·Journal of Neurosurgery·A AsaiK Takakura
Sep 1, 1980·Journal of Neurosurgery·W R AndersonS H Tsai
Aug 1, 1997·Clinical Neurology and Neurosurgery·T T Lee, L K Page
Feb 13, 1999·Neuroradiology·H G BrownR R Lee
Mar 17, 2004·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Shimareet KumarRobert Keating
Apr 2, 2004·Pediatric Radiology·Boris P EckhardtKlaus U Wentz
Nov 13, 2004·Applied Immunohistochemistry & Molecular Morphology : AIMM·Eduardo-Alfredo Zevallos-GiampietriCarlos Barrionuevo
Apr 5, 2005·Pediatric Hematology and Oncology·Arnold C Paulino, B Zach Fowler
Apr 22, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Chusana SuankratayHenry Wilde
May 27, 2005·Auris, Nasus, Larynx·Timur AkcamSertac Yetiser
Jun 9, 2005·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·Ruth Board, Gordon C Jayson
Sep 30, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David R D'AdamoRobert G Maki
Feb 8, 2006·Journal of Clinical Pathology·C KerstingH Buerger
Mar 25, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·C S MathiesonS Jamal
May 27, 2009·International Journal of Radiation Oncology, Biology, Physics·Thomas FlanneryDouglas Kondziolka
Aug 5, 2009·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Sumit JhasJames T Rutka
Sep 15, 2009·Indian Journal of Cancer·A JainK C Lakshmaiah
Dec 5, 2009·The Lancet Oncology·Frédéric AmantIgnace Vergote
Mar 13, 2010·Journal of Pediatric Hematology/oncology·Sweta GuptaSachin S Jogal
Aug 3, 2010·International Journal of Clinical Oncology·Shanthi SivendranMyra F Barginear
Nov 11, 2010·Journal of Neuro-oncology·Yasunori FujimotoToshiki Yoshimine
Mar 2, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Narothama Reddy AeddulaAlireza Hosseinnezhad
Mar 26, 2011·Pathology Research International·Bibianna PurginaLiron Pantanowitz
May 7, 2011·Clinical Neuropathology·M AlmubaslatZ Xiong
Aug 23, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M AgulnikR S Benjamin
Jan 26, 2013·Journal of Medical Case Reports·Claudio RidolfiAlberto Ravaioli
Mar 13, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Alice Boyd SmithElisabeth J Rushing
Mar 13, 2014·The Lancet Oncology·Ian JudsonUNKNOWN European Organisation and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Apr 23, 2014·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Michèle AumüllerJoachim K Krauss
Mar 26, 2016·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Carla BartoschJosé M Lopes
Jun 30, 2016·Clinical Nuclear Medicine·Aurora Crespo-JaraAntonio Brugarolas Masllorens
Aug 25, 2016·Journal of Oncology Practice·Peter J PolewskiDavid E Marinier
Sep 14, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christopher W RyanPatrick Schöffski
Dec 21, 2016·Drugs·Matt Shirley

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.