Primary Intracranial Leptomeningeal Melanomatosis

Journal of Korean Neurosurgical Society
Do-Hyoung KimMee Joo

Abstract

Primary intracranial malignant melanoma is a very rare and highly aggressive tumor with poor prognosis. A 66-year-old female patient presented a headache that had been slowly progressing for several months. A large benign pigmented skin lesion was found on her back. A brain MRI showed multiple linear signal changes with branching pattern and strong enhancement in the temporal lobe. The cytological and immunohiostochemical cerebrospinal fluid examination confirmed malignant melanoma. A biopsy confirmed that the pigmented skin lesion on the back and the conjunctiva were benign nevi. We report a case of primary intracranial malignant melanoma and review relevant literatures.

Citations

Jun 21, 2016·World Neurosurgery·Alexandru SzathmariCarmine Mottolese
Sep 3, 2016·World Journal of Surgical Oncology·Marta Troya-CastillaFrancisco Javier Márquez-Rivas
Jun 20, 2017·The Neuroradiology Journal·Sabina AslanIsin Unal Cevik
Dec 1, 2020·The Journal of Veterinary Medical Science·Chih-Ching WuYa-Pei Chang
Aug 4, 2021·Indian Journal of Pathology & Microbiology·Pooja K GajariaNaina A Goel

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biopsy

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