PMID: 8941002Dec 1, 1996Paper

Primary intrapulmonary meningiomas. A clinicopathologic and immunohistochemical study of ten cases

Cancer
C A MoranM N Koss

Abstract

Primary intrapulmonary meningiomas are rare, and their occurrence has been reported in the literature only sporadically. The clinical, pathologic, and immunohistochemical features of ten cases of primary intrapulmonary meningioma were reviewed. The patients were 4 women and 6 men between the ages of 30 and 72 years (mean age: 51 years). In nine patients, the lung tumor was found during a routine chest radiographic study. The only patient with clinical symptomatology was a man who presented with a persistent cough of 45 days' duration. None of the patients had a previous history of central nervous system (CNS) meningioma or other tumor at the time of diagnosis. Macroscopically, the neoplasms were described as soft, white, well circumscribed lesions that ranged in size from 1.5 cm to 4 cm in greatest dimension. No predilection for any particular lobe or segment of lung was observed. Histologically, all the tumors showed the characteristic growth pattern of CNS meningiomas and were classified accordingly. Seven tumors were transitional meningiomas, and three were fibrous meningiomas. Psammoma bodies were observed in 50% of the tumors. Immunohistochemically, six cases showed positive staining for Epithelial Membrane Antigen (EMA) a...Continue Reading

Citations

Jun 25, 2008·The Annals of Thoracic Surgery·Daniel J RosenCliff P Connery

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