Primary invasive micropapillary carcinoma of the stomach

Pathology International
Masayuki ShimodaHitoshi Sugiura

Abstract

Reported herein is the case of a 74-year-old man with an unusual gastric carcinoma that developed at the lesser curvature of the stomach. The tumor consisted of small clusters of carcinoma cells surrounded by clear spaces, with histopathology similar to invasive micropapillary carcinoma (IMPC) of the breast. The carcinoma cells, which had downregulation of E-cadherin expression, invaded the subserous tissue and metastasized to the perigastric lymph nodes. IMPC, an unusual subtype of invasive breast carcinoma, is known to have frequent lymph node metastases, resulting in a poor clinical outcome. Although IMPC has been reported in breast, urinary bladder, ureter, lung, salivary gland and colon, to the best of the authors' knowledge this is the first report of IMPC arising in the stomach. Presented here are the clinicopathological features of primary IMPC of the stomach.

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Citations

Mar 9, 2013·Medical Molecular Morphology·Yuji OhtsukiMutsuo Furihata
Oct 12, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Takeo FujitaTaira Kinoshita
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Feb 25, 2014·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Qingfu ZhangXueshan Qiu
Jan 5, 2016·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Kei TomiharaMakoto Noguchi
Nov 30, 2014·Clinical Journal of Gastroenterology·Hiroki TanakaGen Watanabe
Apr 30, 2016·Archives of Pathology & Laboratory Medicine·Sangjeong Ahn, Do Youn Park
May 20, 2015·World Journal of Gastroenterology : WJG·Valeria BarresiRosario Alberto Caruso
Aug 12, 2014·Oncology Reports·Tadashi YoshizawaHiroshi Kijima

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