Primary Leiomyosarcoma of the Gallbladder

Case Reports in Oncological Medicine
Anwar ChammoutGhefar Omar

Abstract

Leiomyosarcoma (LMS) of the gallbladder is an extremely rare entity. Most reported cases were mistakenly diagnosed preoperatively as cholecystitis with or without cholelithiasis. We believe that our article demonstrates the 5th case of gallbladder LMS that was suspected preoperatively to be malignant rather than cholecystitis, which fortunately led to radical resection of the tumor instead of simple cholecystectomy. However, the definitive diagnosis relies exclusively on histological and immunohistochemical techniques. We present a case of a 62-year-old Caucasian female complaining of signs and symptoms suggestive for cholecystitis. On ultrasonography, the gallbladder appeared enlarged and filled with a necrotic mass; thus, the presence of adenocarcinoma was suspected. Multislice Computerized Tomography (MSCT) demonstrated no distant metastasis. An extensive radical cholecystectomy was performed, and histological techniques confirmed a leiomyosarcoma diagnosis. In addition, adjuvant chemotherapy of doxorubicin and ifosfamide was administrated. The patient was on follow-up for 2 years and is doing well till date. The discrimination of gallbladder sarcoma preoperatively remains a clinical and radiological challenge. Although radi...Continue Reading

References

Jul 1, 1990·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·C FotiadisM Sechas
Mar 1, 1984·Journal of Clinical Ultrasound : JCU·J C CoelhoR R Moreira
Jul 11, 1998·Acta Oncologica·D A ZeigR J Fitzgibbons
Mar 2, 2010·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·A García MarínF Turégano Fuentes
Aug 18, 2012·Case Reports in Gastrointestinal Medicine·Ajay SavlaniaY K Chawla
Dec 12, 2012·Journal of the Korean Surgical Society·Eun Young ParkKoon Taek Han

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BETA
dissection
SMA

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