Primary lipid cardiomyopathy

Virchows Archiv. A, Pathological Anatomy and Histopathology
A ZimmermannF Stocker

Abstract

In this communication, we describe an isolated, apparently congenital cardiomyopathy (CMP) characterized by the accumulation of stainable lipid in mitochondria of cardiomyocytes. This lesion, which we term primary lipid cardiomyopathy, has not been reported so far. The structural alteration was associated with progressive heart failure, leading to death at the age of 3 years, and with massive hypertrophy of myocardium. Lipid storage in heart muscle cells resulted in an impressive yellow to orange color of the myocardium. We suggest that this type of primary CMP may represent a new member within the group of mitochondrial CMPs. Possible pathogenic mechanisms are discussed.

References

Feb 1, 1975·Neurology·D H VanDykeS Dimauro
Mar 1, 1975·Journal of the Neurological Sciences·F JerusalemG Baumgartner
Jan 1, 1979·Muscle & Nerve·A MirandaL P Rowland
Feb 1, 1978·Neurology·Z H HartR Ayyar
Mar 8, 1975·British Medical Journal·I ChanarinG Stewart
Jan 1, 1989·Acta Neuropathologica·A OldforsB Kristiansson
Jan 1, 1989·The American Journal of Cardiology·A M MaglioccoW M Lester
Jan 1, 1986·Annals of the New York Academy of Sciences·S TakamiyaW Ruitenbeek
Dec 1, 1988·Annals of Neurology·Y KogaK Nihei
Nov 1, 1988·Human Pathology·R A Franciosi, A Singh
Apr 1, 1986·Australian and New Zealand Journal of Medicine·F MechlerJ N Walton
Jan 1, 1987·Acta Neuropathologica·A OldforsB O Eriksson
Nov 1, 1986·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·W R TreemJ B Watkins
Jun 1, 1985·Annals of Neurology·S DiMauroD C DeVivo
Feb 1, 1986·Archives of Neurology·J E CarrollJ I Trefz
Dec 1, 1983·Journal of the Neurological Sciences·P G BarthM A Sobotka-Plojhar
Jan 10, 1983·FEBS Letters·J M TagerL Wojtczak
Jan 1, 1983·Virchows Archiv. A, Pathological Anatomy and Histopathology·G Hübner, R Grantzow
Mar 1, 1983·The Journal of Pediatrics·S I GoodmanS Berlow
Jun 23, 1983·The New England Journal of Medicine·C MeierJ Geissbühler

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Seema MitalThomas H Hintze
Circulation Journal : Official Journal of the Japanese Circulation Society
Jin Hee OhIn Sook Park
© 2021 Meta ULC. All rights reserved