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Primary lymphoma of the central nervous system: epidemiology, pathology and current approaches to diagnosis, prognosis and treatment

Leukemia & Lymphoma

Oct 15, 2008

James L RubensteinStefania Pittaluga

Abstract

An overview of the current approaches to the management of patients with primary central nervous system lymphoma (PCNSL) is provided. Although accumulating evidence demonstrates that PCNSL is a curable type of brain tumor, in many cases establishing the diagnosis and overcoming chemothe...read more

Mentioned in this Paper

Study
Monoclonal Antibodies
Pathogenic Aspects
Biochemical Pathway
Diagnostic Radiology Modality
Pathogenesis
Effects of Radiation
Entire Central Nervous System
Antiretroviral Therapy
Antineoplastic Chemotherapy Protocols
Paper Details
References
  • References38
  • Citations33
1234
  • References38
  • Citations33
1234

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Primary lymphoma of the central nervous system: epidemiology, pathology and current approaches to diagnosis, prognosis and treatment

Leukemia & Lymphoma

Oct 15, 2008

James L RubensteinStefania Pittaluga

PMID: 18821432

DOI: 10.1080/10428190802311441

Abstract

An overview of the current approaches to the management of patients with primary central nervous system lymphoma (PCNSL) is provided. Although accumulating evidence demonstrates that PCNSL is a curable type of brain tumor, in many cases establishing the diagnosis and overcoming chemothe...read more

Mentioned in this Paper

Study
Monoclonal Antibodies
Pathogenic Aspects
Biochemical Pathway
Diagnostic Radiology Modality
Pathogenesis
Effects of Radiation
Entire Central Nervous System
Antiretroviral Therapy
Antineoplastic Chemotherapy Protocols

Similar Papers Found In These Feeds

Immune Therapies In Cancer

Immunotherapy in cancer is used to help the immune system fight against invading cancer cells. It is used to slow the progression of the disease and prevent metastasis while enhancing the immune response. There are different types, including monoclonal antibodies and checkpoint inhibitors. Here is the latest research on immune therapies in cancer.

Neurotoxicity, Inflammation & Neuroprotection

The end result of the inflammatory process, neurotoxicity and/or neuroprotection, is a function of the fine balance between the two cellular systems, i.e., of the complex signaling relationships between anti-inflammatory neuroprotective factors (neurotrophins and other chemical mediators) and proinflammatory neurotoxic factors (tnf, free radicals, certain cytokines, etc). Here are the latest discoveries pertaining to neurotoxicity, inflammation and neuroprotection.

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How important is whole brain radiotherapy for treatment of primary CNS lymphoma?

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Paper Details
References
  • References38
  • Citations33
1234
  • References38
  • Citations33
1234
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