PMID: 3759532Oct 1, 1986Paper

Primary lymphoma of the thyroid: clinical features, prognostic factors, and results of treatment

International Journal of Radiation Oncology, Biology, Physics
L TupchongC Harmer


This study analyzes the results of 46 cases of biopsy-proven primary lymphoma of the thyroid, localized at diagnosis and treated at the Royal Marsden Hospital between 1948-1980. In all cases, disease was limited to the thyroid and cervical lymph nodes. There were 43 females and 3 males, with a mean age of 64.4 years (median 66 years; range 17-86). A short history (less than 3 months) of a neck mass and local compressive symptoms was the typical presentation. The majority of patients (91%) had adverse histologies, with diffuse histiocytic lymphomas being most common (78%). The overall crude 5-year survival rate was 40%, with 30% of patients surviving beyond 10 years. Disease-free and overall survival were virtually identical, indicating the ineffectiveness of salvage therapy. The important prognostic factors were: size of tumor, fixation, extra-capsular extension, and retrosternal involvement. Survival was not correlated with age, sex, histology, thyroid status, or stage of disease, as defined by the Ann Arbor classification. Patients who had total macroscopic removal of tumor had the highest rate of local control and long survival (p less than 0.005). No significant difference was seen between lobectomy, subtotal or total thyro...Continue Reading


Jan 1, 1977·Cancer·J D BitranJ E Ultmann
Oct 19, 1979·JAMA : the Journal of the American Medical Association·D K Sirota, R L Segal
Apr 1, 1978·American Journal of Surgery·R RossiJ Werber
Oct 1, 1975·The British Journal of Surgery·J S Wade
Feb 1, 1966·The Journal of Experimental Zoology·R Rappaport
Sep 1, 1973·Cancer·S E JonesS A Rosenberg
Oct 1, 1974·Cancer·R J Lukes, R D Collins
Dec 1, 1973·British Medical Journal·M D Staunton, W P Greening
May 1, 1969·Radiology·C C Wang
Jan 1, 1972·Cancer·C FreemanS J Cutler
Apr 1, 1972·Cancer·S E JonesH S Kaplan
Feb 16, 1967·The New England Journal of Medicine·Y FujimotoJ R Brooks
Mar 1, 1969·Radiology·P M Shimkin, R H Sagerman
Nov 1, 1983·Annals of Internal Medicine·J I HamburgerS R Kini
Jan 1, 1983·International Journal of Radiation Oncology, Biology, Physics·M K GospodarowiczT Chua
Dec 15, 1981·Cancer·L Y ChakH S Kaplan
Mar 1, 1982·Head & Neck Surgery·S B KapadiaC G Watson
Jan 1, 1981·World Journal of Surgery·R M DevineP M Banks
Jul 1, 1980·The British Journal of Surgery·R P Grimley, G D Oates
Jan 1, 1953·The Journal of Pathology and Bacteriology·D B BREWER, J W ORR
Nov 1, 1955·The Journal of Clinical Endocrinology and Metabolism·S LINDSAY, M E DAILEY
Jan 1, 1956·The British Journal of Surgery·R L CANNEY
Jan 1, 1957·The Journal of Clinical Endocrinology and Metabolism·B M BLACKL B WOOLNER
Jul 1, 1957·Cancer·A J WALTB M BLACK
Aug 1, 1961·Postgraduate Medical Journal·L ROBERTS
Mar 1, 1961·The British Journal of Surgery·W J METCALFE, G SCLARE

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