Primary mandibular xanthoma: case report

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Melissa Rodrigues de AraujoAllan Fernando Giovanini

Abstract

Xanthoma is a very rare bone tumor, especially in the mandible, that can be associated with metabolic diseases such as hyperlipidemia. A 14-year-old girl presented with a non-corticated unilocular radiolucent lesion observed on panoramic radiography. The lesion was located between the roots of the left first and second premolar teeth, extending from the cervical to the apical region, measuring approximately 1 cm in greatest dimension. An excisional biopsy revealed foam cells and occasional nonfoamy mononuclear macrophage-like cells spread among a discrete fibrous stroma. Immunohistochemically, the xanthomatous cells were CD68 and vimentin positive, focally positive for S100, CD1a, and CD3 and negative for AE1/AE3, CD20, CD117, and HMB45. Hematologic and biochemical investigations ruled out systemic disease.

References

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Citations

Oct 25, 2016·Head and Neck Pathology·Yeshwant B RawalJames M Hall
Jul 30, 2019·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·José Alcides Almeida de ArrudaRicardo Alves Mesquita
Oct 22, 2019·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·E DavidA Laquievre

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