Primary non-Hodgkin's lymphoma of the breast. A case report

Cirugia y cirujanos
José Sebastián Villalón-LópezPedro Gonzalo Méndez-Sashida

Abstract

Primary breast lymphomas, a rare subtype of non-Hodgkin's lymphoma, represent 0.04 to 0.5% of all breast cancers, 0.38 to 0.7% of all lymphomas, and 1.7 to 2.2% of extranodal lymphomas. The treatment choice is based on chemotherapy containing anthracycline and rituximab. Surgery is limited to being less invasive and only for diagnostic purposes. Radiotherapy has an important role as consolidation therapy, particularly in patients with negative nodes. A 70 year old woman with a breast nodule in the left upper outer quadrant, with slow growth, expansive, painless, and accompanied by skin changes, malaise, weight loss, fatigue, chill, and sweating. There was tissue replacement by the mammary gland tumour, skin changes due to invasion, and a 5cm axillary lymphadenopathy. The mammography showed skin thickening and a dense pattern of 80% of breast tissue replacement, and the lymphadenopathy with loss of radiolucent centre and soft tissue invasion. The biopsy confirmed a diffuse high grade large cell lymphoma. She received an Rituximab (R-CHOP) chemotherapy scheme and radiotherapy with tangential and supraclavicular and axillary fields. After completing the chemotherapy, the patient is on follow-up, and at 15 months she is alive witho...Continue Reading

References

Jan 1, 1972·Cancer·C FreemanS J Cutler
Sep 17, 2005·Oncology·Agustin AvilésSergio Cleto
Oct 4, 2007·Radiology·Wei Tse YangHomer A Macapinlac
Oct 13, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G RyanUNKNOWN International Extranodal Lymphoma Study Group
May 29, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A AvivA Polliack
Oct 25, 2013·Journal of breast cancer·Euddeum ShimGil Soo Son
Dec 11, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Roberto N MirandaL Jeffrey Medeiros
Aug 8, 2014·Insights Into Imaging·K N GlazebrookR T Fazzio

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.