Primary ovarian trabecular carcinoid tumour: a case report with an immunohistochemical study and a review of the literature

Archives of Gynecology and Obstetrics
J De la TorreA Gil

Abstract

Primary ovarian carcinoid tumours are uncommon neoplasias. There are distinct histological types with different behaviours: insular, trabecular, mucinous and mixed. The trabecular subtype is very rare and unlike other carcinoid subtypes, it is characterised by the absence of a clinical carcinoid syndrome and has been related with a better prognosis than the others. No distant metastases have yet been reported. We present a case of a 76-year-old woman diagnosed with a left ovarian tumour. She underwent a radical hysterectomy with bilateral salpingo-oophorectomy and regional lymph node clearance. Histology revealed an ovarian trabecular carcinoid tumour and no adjuvant treatments were performed. The patient is alive and free of disease 70 months following diagnosis. Immunohistochemical staining for p53 protein, and a comparative study with other subtypes of ovarian carcinoid tumours (insular and mucinous) is discussed in this report.

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Citations

Dec 5, 2014·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Kristen E MullerAlan R Schned
Jul 24, 2010·Archives of Gynecology and Obstetrics·Xuejuan BaiQi Yu
Sep 22, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·H-Y LeeV A Fabian
Jun 8, 2006·The British Journal of Oral & Maxillofacial Surgery·Pavel DundrJirí Mazánek
Feb 9, 2018·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Veronica A PredaAshley B Grossman
Oct 25, 2014·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Nicholas Simon ReedIsabelle Ray-Coquard
Mar 1, 2012·Archives of Pathology & Laboratory Medicine·Melissa A GrilliotXiuli Liu
Oct 7, 2020·Medicine·Li-Rong ZhaiMan-Hua Cui

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