Primary pontine hemorrhage in the acute stage: clinical features and a proposed new simple scoring system

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Toshinari MeguroShigeki Nishino

Abstract

It is important to evaluate the likelihood of fatality in patients with acute primary pontine hemorrhage (PPH) in emergency departments. We aimed to evaluate the clinical symptoms and computed tomography findings of PPH to develop a simple grading scale for predicting the mortality of PPH. Records of 101 consecutive patients admitted to our hospital with acute PPH between June 1, 2006, and January 31, 2014, were retrospectively reviewed. Independent predictors of 30-day mortality were identified by univariate and multivariate logistic regression analyses. A simple and easy clinical score (PPH score) was developed from independent factors to predict mortality in acute PPH. The PPH score was compared with the established intracerebral hemorrhage (ICH) score, which served as the reference scoring system. Overall mortality rate 30 days after onset was 58.4% (59 of 101). Factors independently associated with 30-day mortality were Glasgow Coma Scale (GCS) score of 6 or less (P = .0051), absence of pupillary light reflex (P = .0003), and blood glucose of 180 mg/dL or greater (P = .0312). The PPH score was the sum of independent factors, which were assigned 1 point each. The area under the receiver operating characteristic curve for pr...Continue Reading

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Citations

Feb 19, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Chuanyuan TaoChao You
Dec 10, 2016·Stroke; a Journal of Cerebral Circulation·Kaibin HuangSuyue Pan
Jun 4, 2019·Journal of Neurointerventional Surgery·Ulf NeubergerMarkus Alfred Möhlenbruch
Apr 23, 2019·European Stroke Journal·Réza Behrouz

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