Primary pulmonary lymphoepithelioma-like carcinoma initially diagnosed as squamous metaplasia: A case report and literature review

Oncology Letters
Yasha LiangFengming Luo

Abstract

A mass was detected in the middle lobe of the right lung of a 58-year-old female. The patient did not present any symptoms and was a nonsmoker. Diagnostic evaluation revealed squamous metaplasia in the middle lobe of the right lung. During surgery, a tumor was identified, which was diagnosed as a lymphoepithelioma-like carcinoma (LELC). LELCs have been mainly reported in the Asian population and are associated with the Epstein-Barr virus (EBVs), while they are not associated with smoking. Squamous metaplasia, which is the basis of squamous cell carcinoma, differs from LELC in the therapeutic methods used and the prognostic evaluation. Squamous metaplasia requires regular follow-up in out-patient clinics, while pulmonary LELC is treated by surgery and chemotherapy. Therefore, distinguishing between LELCs and other nonmalignant or premalignant conditions is essential.

References

Sep 1, 1991·Journal of Surgical Oncology·B MillerR Kowalski
Dec 1, 1987·Journal of Surgical Oncology·L R BéginL Panasci
Nov 1, 1995·The Journal of Pathology·M P WongK H Fu
Nov 1, 1995·Pathology, Research and Practice·W WöckelA Morresi
Mar 1, 1997·Der Pathologe·W WöckelA Morresi-Hauf
Mar 8, 2000·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·A BarrosoB Parente
Apr 27, 2000·Critical Reviews in Oncology/hematology·J L Hsu, S L Glaser
Aug 15, 2000·American Journal of Clinical Pathology·A J HanY S Zong
May 23, 2002·The American Journal of Surgical Pathology·Yih-Leong ChangYung-Chie Lee
Jul 10, 2002·International Journal of Oral and Maxillofacial Surgery·T L ChowS P Y Kwok
Jun 27, 2003·Human Pathology·Patrizia MorbiniUmberto Magrini
Apr 7, 2004·Virchows Archiv : an International Journal of Pathology·Francisco Miguel Izquierdo-GarcíaManuel Benéitez-Alvarez
Jul 15, 2004·Annals of the New York Academy of Sciences·Roger K C NganC K Law
Jan 18, 2006·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Naoyuki YoshinoKazuo Shimizu
Apr 25, 2006·AJR. American Journal of Roentgenology·Joseph M HoxworthMichael B Gotway
Aug 19, 2006·Respirology : Official Journal of the Asian Pacific Society of Respirology·James C HoWah K Lam
Mar 17, 2010·Journal of the American Academy of Dermatology·Rui AokiShinji Shimada
Mar 16, 2012·General Thoracic and Cardiovascular Surgery·Satona TanakaHiroshi Date
Nov 23, 2013·Tuberculosis and Respiratory Diseases·Jae Seok JeongYong Chul Lee
Dec 5, 2013·Clinical Nuclear Medicine·Aisheng DongChangjing Zuo
Mar 13, 2014·Diagnostic Cytopathology·Asmaa Gaber Abdou, Nancy Youssef Asaad
Aug 15, 2014·Indian Journal of Pathology & Microbiology·Yanfeng BaiHua Xiang

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