Primary Sarcoma of the Lung - Prognostic Value of Clinicopathological Characteristics of 26 Cases

Anticancer Research
Jose Duran-MorenoKonstantinos Syrigos

Abstract

Primary sarcomas of the lung (PSL) represent a rare, largely unknown entity. We herein present a retrospective study of 26 patients diagnosed with PSL. For a period of 10 years, the records of patients from 5 centers were gathered and analyzed. Median age at diagnosis was 61.96 years (range=31-75 years). Eight patients (33.33%) had mediastinal node invasion (MNI). From 17 patients (70.83%) with localized disease, 11 patients (64.70%) underwent surgery. Recurrence rate was 72.72%. Median disease-free interval was 15 months. The median overall survival (OS) of patients with metastatic disease was 4 months and 10 months for the whole population. Only surgery had an impact on survival. Prognosis of PSL is somber. The high proportion of patients with MNI at diagnosis may serve as an indication for surgical evaluation of mediastinum and raises the question whether patients with locoregional PSL should be treated with a more aggressive approach.

Citations

Aug 12, 2021·Journal of Chest Surgery·Muhammet SayanAbdullah Irfan Tastepe

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