Primary small intestinal malignant tumors: survival analysis of 48 postoperative patients

Journal of Clinical Gastroenterology
Jun CaoJin Li

Abstract

Primary small intestinal malignant tumor is relatively uncommon compared to gastric and colorectal cancer. It is difficult to make an early diagnosis due to the atypical primary symptoms and lack of effective diagnostic methods. To analyze the relationship between the prognoses, histologic type, and therapeutic strategy in postoperative patients with small intestinal tumor. The parameters that affect survival were evaluated using multivariate Cox analysis in 48 cases of small intestinal tumor (confirmed by operation and pathology) for the past 10 years. The overall survival (OS) of all 48 cases after surgery was 28 months. The 5-year postoperative survival rate for all of the 48 cases was 27.1%. The median OS for all the 20 stage II/III patients who received adjuvant chemotherapy was 28 months, whereas the median OS for the 15 patients who did not receive the therapy was 37 months (P=0.276). The median time to progression for 8 patients with adenocarcinoma who received 5-fluorouracil or platinum-based palliative chemotherapy was 7 months, whereas for the patients who did not receive the therapy it was 3 months (P=0.06). The result of multivariate analyses showed that only the clinical stage was significantly correlated with OS ...Continue Reading

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Citations

May 12, 2010·Annals of Surgical Oncology·Michael B NichollGagandeep Singh
Mar 25, 2014·Cancer Investigation·Xiao-Chuan GuoLi Bai
Nov 23, 2010·American Journal of Clinical Pathology·Owen T M ChanHanlin L Wang
Dec 15, 2010·Journal of the Korean Society of Coloproctology·Chang Hyun KimSeong Taek Oh
May 8, 2010·Expert Opinion on Pharmacotherapy·Guru Trikudanathan, Constantin A Dasanu

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