Primary spinal glioma in children: Results from a referral pediatric institution in Shanghai

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
J KhalilJ Mawei

Abstract

Primary spinal cord glioma is a rare entity especially in children; accounting for less than 10% of all central nervous system tumors. Low grade is the most reported subtype. Treatment modalities have largely evolved; large improvements have been made in the surgical field but also in both of radiotherapy and chemotherapy. Nevertheless, the optimal treatment is yet to be defined. A chart review of 11 pediatric patients with a diagnosis of low grade spinal cord glioma at Xhinhua hospital in Shanghai was conducted. A statistical package for Social Sciences Package (SPSS) was used for analysis. Means and standard deviations were calculated. The Kaplan-Meier method was used to analyze overall survival and progression-free survival. The mean age was 6.7 years (range: 6 months-14.3 years). Revealing symptoms were variable and slowly progressive. The mean duration of symptoms prior to diagnosis was of 7±3.2 months. Astrocytoma was the most commonly reported histological type (seven cases, 63.6%), ependymomas were reported in three cases (27.3%). Surgery was performed in all patients. Subtotal resection concerned the majority of patients (nine patients, 81.8%). Adjuvant radiotherapy was indicated in all cases. A total dose of 39.6Gy wa...Continue Reading

Citations

Nov 2, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·F LakhdarF M Chaoui
Oct 24, 2019·Journal of Neuro-oncology·Steven S CareyIbrahim Qaddoumi

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