PMID: 6990971May 13, 1980Paper

Primary structure of AUA-specific isoleucine transfer ribonucleic acid from Escherichia coli

Biochemistry
Y KuchinoS Nishimura

Abstract

The nucleotide sequence of an E. coli isoleucine tRNA (tRNAIle minor) specific for the codon AUA was determined by postlabeling procedures using only 2.5 micrograms (0.05 A260 unit) of the material. The sequence was pG-G-C-C-C-C-U-s4U-A-G-C-U-C-A-G-U-Gm-G-D-D-A-G-A-G-C-A-A-G-C-G-A-C-U-N+-A-U-t6A-A-psi-C-G-C-U-U-G-m7G-acp3U-C-G-C-U-G-G-T-psi-C-A-A-G-U-C-C-A-G-C-A-G-G-G-G-C-C-A-C-C-AOH. The nucleotide sequences in the regions of the D arm and T psi C arm of tRNAIle minor were quite similar to the corresponding regions of tRNAIle major. However, the sequences in the CCA stem and anticodon stem of tRNAIle minor were different from those of tRNAIle major. The overall homology between the two isoleucine tRNAs was 68%. E. coli tRNALys, tRNAMet, tRNAValIIA and tRNAArg also have relatively high sequence homology with tRNAIle minor.

References

Jan 1, 1978·Nucleic Acids Research·R E LockardU L RajBhandary
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·D A Peattie
Aug 10, 1979·Nucleic Acids Research·Y KuchinoS Nishimura
Feb 1, 1977·European Journal of Biochemistry·M SilberklangU L Rajbhandary
Aug 1, 1977·Nucleic Acids Research·H Donis-KellerW Gilbert
Jul 6, 1978·Nature·J Stanley, S Vassilenko
Oct 1, 1978·Nucleic Acids Research·A G Bruce, O C Uhlenbeck
Oct 1, 1977·Nature·A SimoncsitsH Guilley
May 21, 1971·Biochemical and Biophysical Research Communications·M Yarus, B G Barrell
Dec 20, 1976·Biochemical and Biophysical Research Communications·W M JouW Fiers

❮ Previous
Next ❯

Citations

Jan 1, 1983·Journal of Molecular Evolution·T H Jukes
Dec 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·M DavidG Kaufmann
Jul 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·Y KuchinoS Nishimura
Mar 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·M J Fedor, O C Uhlenbeck
Sep 13, 2008·Nucleosides, Nucleotides & Nucleic Acids·Kailas D Sonawane, Ravindra Tewari
Oct 25, 1982·Nucleic Acids Research·Y KuchinoS Nishimura
Aug 25, 1983·Nucleic Acids Research·C J Green, B S Vold
Dec 20, 1983·Nucleic Acids Research·C C HsuChenD T Dubin
May 11, 1984·Nucleic Acids Research·B R VaniS Nishimura
May 25, 1988·Nucleic Acids Research·G H LearnM T Clegg
Sep 25, 1981·Nucleic Acids Research·Y KuchinoS Nishimura
Apr 9, 1981·Nature·S AndersonI G Young
Sep 21, 1981·Journal of Theoretical Biology·R Mikelsaar
Mar 5, 1987·Journal of Molecular Biology·M D MendenhallM R Culbertson
May 1, 1986·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·U Lagerkvist
Nov 21, 1983·Journal of Theoretical Biology·R Mikelsaar
Jul 30, 1990·Journal of Molecular Biology·J D PuglisiI Tinoco
Jun 14, 1991·Biochemical and Biophysical Research Communications·K Kusama-EguchiK Igarashi
May 15, 1990·Archives of Biochemistry and Biophysics·Z PengK Igarashi
Aug 1, 1991·Archives of Biochemistry and Biophysics·K Kusama-EguchiK Igarashi
Oct 1, 1991·Biochemistry·S C Dahm, O C Uhlenbeck
Dec 8, 1992·Biochemistry·M J Fedor, O C Uhlenbeck
Jul 29, 2015·Integrative Biology : Quantitative Biosciences From Nano to Macro·Kailas D Sonawane, Susmit B Sambhare
Jan 21, 1988·Nature·J D PuglisiI Tinoco
Jun 1, 1994·Molecular and Cellular Biology·H M DunstanK U Sprague

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.