PMID: 2487283Jan 1, 1989Paper

Primary structure of zeta-crystallin protein from guinea pig. Its similarity to the enzyme alcohol dehydrogenase

Lens and Eye Toxicity Research
T Borrás, A Rodokanaki

Abstract

The primary structure of zeta-crystallin, a guinea pig lens specific protein, was obtained by cloning the copy of its mRNA from a 0-1 week old cDNA lens library. The protein is 328 amino acids long and 34% of its secondary structure appears in alpha-helical conformation. Comparison of the zeta-crystallin sequence with the sequences of the protein data base bank, revealed the similarity of this lens protein to the enzymes of the long-chain zinc-containing alcohol dehydrogenase family.

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